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Lacticaseibacillus casei Strain T21 Attenuates Clostridioides difficile Infection in a Murine Model Through Reduction of Inflammation and Gut Dysbiosis With Decreased Toxin Lethality and Enhanced Mucin Production
Clostridioides difficile is a major cause of diarrhea in patients with antibiotic administration. Lacticaseibacillus casei T21, isolated from a human gastric biopsy, was tested in a murine C. difficile infection (CDI) model and colonic epithelial cells (Caco-2 and HT-29). Daily administration of L....
Autores principales: | Panpetch, Wimonrat, Phuengmaung, Pornpimol, Cheibchalard, Thanya, Somboonna, Naraporn, Leelahavanichkul, Asada, Tumwasorn, Somying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672038/ https://www.ncbi.nlm.nih.gov/pubmed/34925261 http://dx.doi.org/10.3389/fmicb.2021.745299 |
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