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Metabolic adaptation to the chronic loss of Ca(2+) signaling induced by KO of IP(3) receptors or the mitochondrial Ca(2+) uniporter

Calcium signaling is essential for regulating many biological processes. Endoplasmic reticulum inositol trisphosphate receptors (IP(3)Rs) and the mitochondrial Ca(2+) uniporter (MCU) are key proteins that regulate intracellular Ca(2+) concentration. Mitochondrial Ca(2+) accumulation activates Ca(2+)...

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Detalles Bibliográficos
Autores principales:	Young, Michael P., Schug, Zachary T., Booth, David M., Yule, David I., Mikoshiba, Katsuhiko, Hajnόczky, Gyӧrgy, Joseph, Suresh K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672050/ https://www.ncbi.nlm.nih.gov/pubmed/34801549 http://dx.doi.org/10.1016/j.jbc.2021.101436

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