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Pseudo-188D: Phage Protein Prediction Based on a Model of Pseudo-188D
Phages have seriously affected the biochemical systems of the world, and not only are phages related to our health, but medical treatments for many cancers and skin infections are related to phages; therefore, this paper sought to identify phage proteins. In this paper, a Pseudo-188D model was estab...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672092/ https://www.ncbi.nlm.nih.gov/pubmed/34925468 http://dx.doi.org/10.3389/fgene.2021.796327 |
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author | Gu, Xiaomei Guo, Lina Liao, Bo Jiang, Qinghua |
author_facet | Gu, Xiaomei Guo, Lina Liao, Bo Jiang, Qinghua |
author_sort | Gu, Xiaomei |
collection | PubMed |
description | Phages have seriously affected the biochemical systems of the world, and not only are phages related to our health, but medical treatments for many cancers and skin infections are related to phages; therefore, this paper sought to identify phage proteins. In this paper, a Pseudo-188D model was established. The digital features of the phage were extracted by PseudoKNC, an appropriate vector was selected by the AdaBoost tool, and features were extracted by 188D. Then, the extracted digital features were combined together, and finally, the viral proteins of the phage were predicted by a stochastic gradient descent algorithm. Our model effect reached 93.4853%. To verify the stability of our model, we randomly selected 80% of the downloaded data to train the model and used the remaining 20% of the data to verify the robustness of our model. |
format | Online Article Text |
id | pubmed-8672092 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-86720922021-12-16 Pseudo-188D: Phage Protein Prediction Based on a Model of Pseudo-188D Gu, Xiaomei Guo, Lina Liao, Bo Jiang, Qinghua Front Genet Genetics Phages have seriously affected the biochemical systems of the world, and not only are phages related to our health, but medical treatments for many cancers and skin infections are related to phages; therefore, this paper sought to identify phage proteins. In this paper, a Pseudo-188D model was established. The digital features of the phage were extracted by PseudoKNC, an appropriate vector was selected by the AdaBoost tool, and features were extracted by 188D. Then, the extracted digital features were combined together, and finally, the viral proteins of the phage were predicted by a stochastic gradient descent algorithm. Our model effect reached 93.4853%. To verify the stability of our model, we randomly selected 80% of the downloaded data to train the model and used the remaining 20% of the data to verify the robustness of our model. Frontiers Media S.A. 2021-12-01 /pmc/articles/PMC8672092/ /pubmed/34925468 http://dx.doi.org/10.3389/fgene.2021.796327 Text en Copyright © 2021 Gu, Guo, Liao and Jiang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Genetics Gu, Xiaomei Guo, Lina Liao, Bo Jiang, Qinghua Pseudo-188D: Phage Protein Prediction Based on a Model of Pseudo-188D |
title | Pseudo-188D: Phage Protein Prediction Based on a Model of Pseudo-188D |
title_full | Pseudo-188D: Phage Protein Prediction Based on a Model of Pseudo-188D |
title_fullStr | Pseudo-188D: Phage Protein Prediction Based on a Model of Pseudo-188D |
title_full_unstemmed | Pseudo-188D: Phage Protein Prediction Based on a Model of Pseudo-188D |
title_short | Pseudo-188D: Phage Protein Prediction Based on a Model of Pseudo-188D |
title_sort | pseudo-188d: phage protein prediction based on a model of pseudo-188d |
topic | Genetics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672092/ https://www.ncbi.nlm.nih.gov/pubmed/34925468 http://dx.doi.org/10.3389/fgene.2021.796327 |
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