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LDL-Based Lipid Nanoparticle Derived for Blood Plasma Accumulates Preferentially in Atherosclerotic Plaque

Apolipoprotein-based drug delivery is a promising approach to develop safe nanoparticles capable of targeted drug delivery for various diseases. In this work, we have synthesized a lipid-based nanoparticle (NPs) that we have called “Aposomes” presenting native apolipoprotein B-100 (apoB-100), the pr...

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Detalles Bibliográficos
Autores principales: Boada, Christian A., Zinger, Assaf, Rohen, Scott, Martinez, Jonathan O., Evangelopoulos, Michael, Molinaro, Roberto, Lu, Madeleine, Villarreal-Leal, Ramiro Alejandro, Giordano, Federica, Sushnitha, Manuela, De Rosa, Enrica, Simonsen, Jens B., Shevkoplyas, Sergey, Taraballi, Francesca, Tasciotti, Ennio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672093/
https://www.ncbi.nlm.nih.gov/pubmed/34926432
http://dx.doi.org/10.3389/fbioe.2021.794676

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