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LDL-Based Lipid Nanoparticle Derived for Blood Plasma Accumulates Preferentially in Atherosclerotic Plaque
Apolipoprotein-based drug delivery is a promising approach to develop safe nanoparticles capable of targeted drug delivery for various diseases. In this work, we have synthesized a lipid-based nanoparticle (NPs) that we have called “Aposomes” presenting native apolipoprotein B-100 (apoB-100), the pr...
Autores principales: | Boada, Christian A., Zinger, Assaf, Rohen, Scott, Martinez, Jonathan O., Evangelopoulos, Michael, Molinaro, Roberto, Lu, Madeleine, Villarreal-Leal, Ramiro Alejandro, Giordano, Federica, Sushnitha, Manuela, De Rosa, Enrica, Simonsen, Jens B., Shevkoplyas, Sergey, Taraballi, Francesca, Tasciotti, Ennio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672093/ https://www.ncbi.nlm.nih.gov/pubmed/34926432 http://dx.doi.org/10.3389/fbioe.2021.794676 |
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