Cargando…

Discover immunotherapy biomarkers from single-cell cytometry data

Currently, identifying novel biomarkers remains a crucial need for cancer immunotherapy. By leveraging single-cell cytometry data, Greene et al. developed an interpretable machine learning method, FAUST, to discover cell populations associated with clinical outcomes.

Detalles Bibliográficos
Autores principales: Ru, Beibei, Jiang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672134/
https://www.ncbi.nlm.nih.gov/pubmed/34950905
http://dx.doi.org/10.1016/j.patter.2021.100384
_version_ 1784615296920715264
author Ru, Beibei
Jiang, Peng
author_facet Ru, Beibei
Jiang, Peng
author_sort Ru, Beibei
collection PubMed
description Currently, identifying novel biomarkers remains a crucial need for cancer immunotherapy. By leveraging single-cell cytometry data, Greene et al. developed an interpretable machine learning method, FAUST, to discover cell populations associated with clinical outcomes.
format Online
Article
Text
id pubmed-8672134
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-86721342021-12-22 Discover immunotherapy biomarkers from single-cell cytometry data Ru, Beibei Jiang, Peng Patterns (N Y) Preview Currently, identifying novel biomarkers remains a crucial need for cancer immunotherapy. By leveraging single-cell cytometry data, Greene et al. developed an interpretable machine learning method, FAUST, to discover cell populations associated with clinical outcomes. Elsevier 2021-12-10 /pmc/articles/PMC8672134/ /pubmed/34950905 http://dx.doi.org/10.1016/j.patter.2021.100384 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Preview
Ru, Beibei
Jiang, Peng
Discover immunotherapy biomarkers from single-cell cytometry data
title Discover immunotherapy biomarkers from single-cell cytometry data
title_full Discover immunotherapy biomarkers from single-cell cytometry data
title_fullStr Discover immunotherapy biomarkers from single-cell cytometry data
title_full_unstemmed Discover immunotherapy biomarkers from single-cell cytometry data
title_short Discover immunotherapy biomarkers from single-cell cytometry data
title_sort discover immunotherapy biomarkers from single-cell cytometry data
topic Preview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672134/
https://www.ncbi.nlm.nih.gov/pubmed/34950905
http://dx.doi.org/10.1016/j.patter.2021.100384
work_keys_str_mv AT rubeibei discoverimmunotherapybiomarkersfromsinglecellcytometrydata
AT jiangpeng discoverimmunotherapybiomarkersfromsinglecellcytometrydata