Cargando…
New interpretable machine-learning method for single-cell data reveals correlates of clinical response to cancer immunotherapy
We introduce a new method for single-cell cytometry studies, FAUST, which performs unbiased cell population discovery and annotation. FAUST processes experimental data on a per-sample basis and returns biologically interpretable cell phenotypes, making it well suited for the analysis of complex data...
Autores principales: | Greene, Evan, Finak, Greg, D'Amico, Leonard A., Bhardwaj, Nina, Church, Candice D., Morishima, Chihiro, Ramchurren, Nirasha, Taube, Janis M., Nghiem, Paul T., Cheever, Martin A., Fling, Steven P., Gottardo, Raphael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672150/ https://www.ncbi.nlm.nih.gov/pubmed/34950900 http://dx.doi.org/10.1016/j.patter.2021.100372 |
Ejemplares similares
-
Merkel cell polyomavirus-specific immune responses in patients with Merkel cell carcinoma receiving anti-PD-1 therapy
por: Miller, Natalie J., et al.
Publicado: (2018) -
IL-7 expands lymphocyte populations and enhances immune responses to sipuleucel-T in patients with metastatic castration-resistant prostate cancer (mCRPC)
por: Pachynski, Russell K, et al.
Publicado: (2021) -
PD-1 and TIGIT coexpression identifies a circulating CD8 T cell subset predictive of response to anti-PD-1 therapy
por: Simon, Sylvain, et al.
Publicado: (2020) -
Multidimensional, quantitative assessment of PD-1/PD-L1 expression in patients with Merkel cell carcinoma and association with response to pembrolizumab
por: Giraldo, Nicolas A., et al.
Publicado: (2018) -
Single-cell RNA-sequencing reveals predictive features of response to pembrolizumab in Sézary syndrome
por: Su, Tianying, et al.
Publicado: (2022)