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Germline RET Leu56Met Variant Is Likely Not Causative of Multiple Endocrine Neoplasia Type 2

Activating variants in the receptor tyrosine kinase REarranged during Transfection (RET) cause multiple endocrine neoplasia type 2 (MEN 2), an autosomal dominantly inherited cancer-susceptibility syndrome. The variant c.166C>A, p.Leu56Met in RET was recently reported in two patients with medullar...

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Detalles Bibliográficos
Autores principales:	Hansen, Anna Reimer, Borgwardt, Line, Rasmussen, Åse Krogh, Godballe, Christian, Poulsen, Morten Møller, Vieira, Filipe G., Mathiesen, Jes Sloth, Rossing, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672160/ https://www.ncbi.nlm.nih.gov/pubmed/34925234 http://dx.doi.org/10.3389/fendo.2021.764512

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