Cargando…

MEOX2 Transcription Factor Is Involved in Survival and Adhesion of Glioma Stem-like Cells

SIMPLE SUMMARY: Glioblastoma is the most common and lethal primary brain tumor for which no curative treatment currently exists. In our previous work, we showed that MEOX2 was associated with a poor patient prognosis but its biological involvement in tumor development remains ill defined. To this pu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tachon, Gaëlle, Masliantsev, Konstantin, Rivet, Pierre, Desette, Amandine, Milin, Serge, Gueret, Elise, Wager, Michel, Karayan-Tapon, Lucie, Guichet, Pierre-Olivier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672280/ https://www.ncbi.nlm.nih.gov/pubmed/34885053 http://dx.doi.org/10.3390/cancers13235943

Ejemplares similares

Cell Cycle Changes after Glioblastoma Stem Cell Irradiation: The Major Role of RAD51
por: Tachon, Gaelle, et al.
Publicado: (2018)

Hippo Signaling Pathway in Gliomas
por: Masliantsev, Konstantin, et al.
Publicado: (2021)

Impact of STAT3 phosphorylation in glioblastoma stem cells radiosensitization and patient outcome
por: Masliantsev, Konstantin, et al.
Publicado: (2017)

Functional invadopodia formed in glioblastoma stem cells are important regulators of tumor angiogenesis
por: Petropoulos, Christos, et al.
Publicado: (2018)

Deciphering Brain Metastasis Stem Cell Properties From Colorectal Cancer Highlights Specific Stemness Signature and Shared Molecular Features
por: Desette, Amandine, et al.
Publicado: (2023)

Dual MGMT inactivation by promoter hypermethylation and loss of the long arm of chromosome 10 in glioblastoma
por: Richard, Sophie, et al.
Publicado: (2020)

The Long Non-Coding RNA HOXA-AS2 Promotes Proliferation of Glioma Stem Cells and Modulates Their Inflammation Pathway Mainly through Post-Transcriptional Regulation
por: Le Boiteux, Elisa, et al.
Publicado: (2022)

Crizotinib targets in glioblastoma stem cells
por: Junca, Audelaure, et al.
Publicado: (2017)

Pathological and Molecular Characteristics of Colorectal Cancer with Brain Metastases
por: Roussille, Pauline, et al.
Publicado: (2018)

Targeted RNA‐sequencing assays: a step forward compared to FISH and IHC techniques?
por: Tachon, Gaëlle, et al.
Publicado: (2019)

Histomolecular characterization of intracranial meningiomas developed in patients exposed to high-dose cyproterone acetate: an antiandrogen treatment
por: Portet, Sylvain, et al.
Publicado: (2019)

O6-Methylguanine-Methyltransferase (MGMT) Promoter Methylation Status in Glioma Stem-Like Cells is Correlated to Temozolomide Sensitivity Under Differentiation-Promoting Conditions
por: Villalva, Claire, et al.
Publicado: (2012)

Microsatellite Instability: Diagnosis, Heterogeneity, Discordance, and Clinical Impact in Colorectal Cancer
por: Evrard, Camille, et al.
Publicado: (2019)

High Intra- and Inter-Tumoral Heterogeneity of RAS Mutations in Colorectal Cancer
por: Jeantet, Marion, et al.
Publicado: (2016)

Detection of Colorectal Cancer and Advanced Adenoma by Liquid Biopsy (Decalib Study): The ddPCR Challenge
por: Junca, Audelaure, et al.
Publicado: (2020)

Widespread overexpression from the four DNA hypermethylated HOX clusters in aggressive (IDHwt) glioma is associated with H3K27me3 depletion and alternative promoter usage
por: Le Boiteux, Elisa, et al.
Publicado: (2021)

New Artificial Intelligence Score and Immune Infiltrates as Prognostic Factors in Colorectal Cancer With Brain Metastases
por: Randrian, Violaine, et al.
Publicado: (2021)

Prognostic value of increase in transcript levels of Tp73 ΔEx2-3 isoforms in low-grade glioma patients
por: Wager, M, et al.
Publicado: (2006)

L1 chimeric transcripts are expressed in healthy brain and their deregulation in glioma follows that of their host locus
por: Pinson, Marie-Elisa, et al.
Publicado: (2022)

A radiosensitizing effect of RAD51 inhibition in glioblastoma stem-like cells
por: Balbous, Anaïs, et al.
Publicado: (2016)

Diagnostic Utility of Immunohistochemical Detection of MEOX2, SOX11, INSM1 and EGFR in Gliomas
por: Soukup, Jiri, et al.
Publicado: (2023)

A mesenchymal glioma stem cell profile is related to clinical outcome
por: Balbous, A, et al.
Publicado: (2014)

MEOX2-mediated regulation of Cathepsin S promotes cell proliferation and motility in glioma
por: Wang, Ji, et al.
Publicado: (2022)

Prognostic molecular markers with no impact on decision-making: the paradox of gliomas based on a prospective study
por: Wager, M, et al.
Publicado: (2008)

EGFR, KRAS, BRAF, and HER-2 molecular status in brain metastases from 77 NSCLC patients
por: Villalva, Claire, et al.
Publicado: (2013)

HSP110 as a Diagnostic but Not a Prognostic Biomarker in Colorectal Cancer With Microsatellite Instability
por: Tachon, Gaelle, et al.
Publicado: (2022)

Analysis of factors influencing molecular testing at diagnostic of colorectal cancer
por: Thiebault, Quentin, et al.
Publicado: (2017)

Transcriptional alterations in glioma result primarily from DNA methylation–independent mechanisms
por: Court, Franck, et al.
Publicado: (2019)

Data on the involvement of Meox1 in balloon-injury-induced neointima formation of rats
por: Wu, Bing, et al.
Publicado: (2017)

Meox2 Haploinsufficiency Accelerates Axonal Degeneration in DBA/2J Glaucoma
por: Buchanan, Rebecca A., et al.
Publicado: (2019)

Mechanisms of MEOX1 and MEOX2 Regulation of the Cyclin Dependent Kinase Inhibitors p21(CIP1/WAF1) and p16(INK4a) in Vascular Endothelial Cells
por: Douville, Josette M., et al.
Publicado: (2011)

Expression of a gap junction protein, connexin43, in a large panel of human gliomas: new insights
por: Crespin, Sophie, et al.
Publicado: (2016)

Mutation in MEOX1 gene causes a recessive Klippel-Feil syndrome subtype
por: Bayrakli, Fatih, et al.
Publicado: (2013)

MEOX1: a novel druggable target that orchestrates the activation of fibroblasts in cardiac fibrosis
por: Schumacher, David, et al.
Publicado: (2021)

Transcription factor mesenchyme homeobox protein 2 (MEOX2) modulates nociceptor function
por: Kokotović, Tomislav, et al.
Publicado: (2022)

Semaphorin, neuropilin and VEGF expression in glial tumours: SEMA3G, a prognostic marker?
por: Karayan-Tapon, L, et al.
Publicado: (2008)

Asymmetric Distribution of GFAP in Glioma Multipotent Cells
por: Guichet, Pierre-Olivier, et al.
Publicado: (2016)

Coronary risk in relation to genetic variation in MEOX2 and TCF15 in a Flemish population
por: Yang, Wen-Yi, et al.
Publicado: (2015)

Facilitation of Bone Healing Processes Based on the Developmental Function of Meox2 in Tooth Loss Lesion
por: Kim, Tae-Young, et al.
Publicado: (2020)

Outcome-based determination of optimal pyrosequencing assay for MGMT methylation detection in glioblastoma patients
por: Quillien, Véronique, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_s7nqa51bo20cupva6jrk0jo52g