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Non-lupus full-house nephropathy: a case series
Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune inflammatory disease. However, some patients may exhibit a histological pattern of kidney injury, with characteristics indistinguishable from lupus nephritis, but without presenting any extrarenal symptoms or serologies suggestiv...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Nefrologia
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672396/ https://www.ncbi.nlm.nih.gov/pubmed/33179718 http://dx.doi.org/10.1590/2175-8239-JBN-2019-0242 |
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author | Silva, Márcia de Oliveira de Oliveira, Patrick Vanttinny Vieira Vale, Pedro Henrique Cavalcante Cunha, Rinadja de Melo Lages, Joyce Santos Brito, Dyego José de Araújo Salgado, Natalino Guedes, Felipe Leite Silva, Gyl Eanes Barros Santos, Ricardo Ferreira |
author_facet | Silva, Márcia de Oliveira de Oliveira, Patrick Vanttinny Vieira Vale, Pedro Henrique Cavalcante Cunha, Rinadja de Melo Lages, Joyce Santos Brito, Dyego José de Araújo Salgado, Natalino Guedes, Felipe Leite Silva, Gyl Eanes Barros Santos, Ricardo Ferreira |
author_sort | Silva, Márcia de Oliveira |
collection | PubMed |
description | Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune inflammatory disease. However, some patients may exhibit a histological pattern of kidney injury, with characteristics indistinguishable from lupus nephritis, but without presenting any extrarenal symptoms or serologies suggestive of SLE. Such involvement has recently been called non-lupus full-house nephropathy. The objective is to report a series of clinical cases referred to the Laboratory of the Federal University of Maranhão that received the diagnosis of "full-house" nephropathy unrelated to lupus, upon immunofluorescence and to discuss its evolution and outcomes. Non-lupus full-house nephropathy represents a diagnostic and therapeutic challenge, because it is a new entity, which still needs further studies and may be the initial manifestation of SLE, isolated manifestation of SLE or a new pathology unrelated to SLE. |
format | Online Article Text |
id | pubmed-8672396 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Sociedade Brasileira de Nefrologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-86723962022-03-22 Non-lupus full-house nephropathy: a case series Silva, Márcia de Oliveira de Oliveira, Patrick Vanttinny Vieira Vale, Pedro Henrique Cavalcante Cunha, Rinadja de Melo Lages, Joyce Santos Brito, Dyego José de Araújo Salgado, Natalino Guedes, Felipe Leite Silva, Gyl Eanes Barros Santos, Ricardo Ferreira J Bras Nefrol Case Report Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune inflammatory disease. However, some patients may exhibit a histological pattern of kidney injury, with characteristics indistinguishable from lupus nephritis, but without presenting any extrarenal symptoms or serologies suggestive of SLE. Such involvement has recently been called non-lupus full-house nephropathy. The objective is to report a series of clinical cases referred to the Laboratory of the Federal University of Maranhão that received the diagnosis of "full-house" nephropathy unrelated to lupus, upon immunofluorescence and to discuss its evolution and outcomes. Non-lupus full-house nephropathy represents a diagnostic and therapeutic challenge, because it is a new entity, which still needs further studies and may be the initial manifestation of SLE, isolated manifestation of SLE or a new pathology unrelated to SLE. Sociedade Brasileira de Nefrologia 2020-11-11 2021 /pmc/articles/PMC8672396/ /pubmed/33179718 http://dx.doi.org/10.1590/2175-8239-JBN-2019-0242 Text en https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Silva, Márcia de Oliveira de Oliveira, Patrick Vanttinny Vieira Vale, Pedro Henrique Cavalcante Cunha, Rinadja de Melo Lages, Joyce Santos Brito, Dyego José de Araújo Salgado, Natalino Guedes, Felipe Leite Silva, Gyl Eanes Barros Santos, Ricardo Ferreira Non-lupus full-house nephropathy: a case series |
title | Non-lupus full-house nephropathy: a case series |
title_full | Non-lupus full-house nephropathy: a case series |
title_fullStr | Non-lupus full-house nephropathy: a case series |
title_full_unstemmed | Non-lupus full-house nephropathy: a case series |
title_short | Non-lupus full-house nephropathy: a case series |
title_sort | non-lupus full-house nephropathy: a case series |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672396/ https://www.ncbi.nlm.nih.gov/pubmed/33179718 http://dx.doi.org/10.1590/2175-8239-JBN-2019-0242 |
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