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Benchmarking UMI-based single-cell RNA-seq preprocessing workflows
BACKGROUND: Single-cell RNA-sequencing (scRNA-seq) technologies and associated analysis methods have rapidly developed in recent years. This includes preprocessing methods, which assign sequencing reads to genes to create count matrices for downstream analysis. While several packaged preprocessing w...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672463/ https://www.ncbi.nlm.nih.gov/pubmed/34906205 http://dx.doi.org/10.1186/s13059-021-02552-3 |