Benchmarking UMI-based single-cell RNA-seq preprocessing workflows

BACKGROUND: Single-cell RNA-sequencing (scRNA-seq) technologies and associated analysis methods have rapidly developed in recent years. This includes preprocessing methods, which assign sequencing reads to genes to create count matrices for downstream analysis. While several packaged preprocessing w...

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Detalles Bibliográficos
Autores principales: You, Yue, Tian, Luyi, Su, Shian, Dong, Xueyi, Jabbari, Jafar S., Hickey, Peter F., Ritchie, Matthew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672463/
https://www.ncbi.nlm.nih.gov/pubmed/34906205
http://dx.doi.org/10.1186/s13059-021-02552-3

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