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Targeted intervention of eIF4A1 inhibits EMT and metastasis of pancreatic cancer cells via c-MYC/miR-9 signaling

BACKGROUND: Owing to the lack of effective treatment options, early metastasis remains the major cause of pancreatic ductal adenocarcinoma (PDAC) recurrence and mortality. However, the molecular mechanism of early metastasis is largely unknown. We characterized the function of eukaryotic translation...

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Detalles Bibliográficos
Autores principales:	Zhao, Yuchong, Wang, Yun, Chen, Wei, Bai, Shuya, Peng, Wang, Zheng, Mengli, Yang, Yilei, Cheng, Bin, Luan, Zhou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672469/ https://www.ncbi.nlm.nih.gov/pubmed/34906136 http://dx.doi.org/10.1186/s12935-021-02390-0

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