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SIRT6 inhibition delays peripheral nerve recovery by suppressing migration, phagocytosis and M2-polarization of macrophages

BACKGROUND: Silent information regulator 6 (SIRT6) is a mammalian homolog of the nicotinamide adenine dinucleotide (NAD)-dependent deacetylase sirtuin family. Prior evidences suggested that the anti-inflammatory function of SIRT6 after spinal cord and brain injury, and it plays a crucial role in mac...

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Detalles Bibliográficos
Autores principales:	Zou, Ying, Zhang, Jiaqi, Xu, Jiawei, Fu, Lanya, Xu, Yizhou, Wang, Xianghai, Li, Zhenlin, Zhu, Lixin, Sun, Hao, Zheng, Hui, Guo, Jiasong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672560/ https://www.ncbi.nlm.nih.gov/pubmed/34906231 http://dx.doi.org/10.1186/s13578-021-00725-y

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