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Mutant Profilin1 Aggregation in Amyotrophic Lateral Sclerosis: An in Vivo Biochemical Analysis

INTRODUCTION: Profilin1 (PFN1) is a ubiquitously expressed protein known for its function as a regulator of actin polymerization and dynamics. A recent discovery linked mutant PFN1 to Amyotrophic Lateral Sclerosis (ALS), which is a fatal and progressive motor neuron disease. We have also demonstrate...

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Detalles Bibliográficos
Autores principales:	Nekouei, Mina, Aliahmadi, Atousa, Kiaei, Mahmoud, Ghassempour, Ali Reza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Iranian Neuroscience Society 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672666/ https://www.ncbi.nlm.nih.gov/pubmed/34925718 http://dx.doi.org/10.32598/bcn.12.2.1631.1

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