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Vinylazaarenes as dienophiles in Lewis acid-promoted Diels–Alder reactions
Described are the first examples of Lewis acid-promoted Diels–Alder reactions of vinylpyridines and other vinylazaarenes with unactivated dienes. Cyclohexyl-appended azaarenes constitute a class of substructures of rising prominence in drug discovery. Despite this, thermal variants of the vinylazaar...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672738/ https://www.ncbi.nlm.nih.gov/pubmed/35024118 http://dx.doi.org/10.1039/d1sc05095h |