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Vinylazaarenes as dienophiles in Lewis acid-promoted Diels–Alder reactions

Described are the first examples of Lewis acid-promoted Diels–Alder reactions of vinylpyridines and other vinylazaarenes with unactivated dienes. Cyclohexyl-appended azaarenes constitute a class of substructures of rising prominence in drug discovery. Despite this, thermal variants of the vinylazaar...

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Detalles Bibliográficos
Autores principales: Davis, Anna E., Lowe, Jared M., Hilinski, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672738/
https://www.ncbi.nlm.nih.gov/pubmed/35024118
http://dx.doi.org/10.1039/d1sc05095h