Detection of Minority Variants and Mixed Infections in Mycobacterium tuberculosis by Direct Whole-Genome Sequencing on Noncultured Specimens Using a Specific-DNA Capture Strategy

Detection of mixed Mycobacterium tuberculosis (MTB) infections is essential, particularly when resistance mutations are present in minority bacterial populations that may affect patients’ disease evolution and treatment. Whole-genome sequencing (WGS) has extended the amount of key information availa...

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Detalles Bibliográficos
Autores principales: Lozano, Nuria, Lanza, Val F., Suárez-González, Julia, Herranz, Marta, Sola-Campoy, Pedro J., Rodríguez-Grande, Cristina, Buenestado-Serrano, Sergio, Ruiz-Serrano, María Jesús, Tudó, Griselda, Alcaide, Fernando, Muñoz, Patricia, García de Viedma, Darío, Pérez-Lago, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673255/
https://www.ncbi.nlm.nih.gov/pubmed/34908457
http://dx.doi.org/10.1128/mSphere.00744-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673255/
https://www.ncbi.nlm.nih.gov/pubmed/34908457
http://dx.doi.org/10.1128/mSphere.00744-21

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