Cargando…

Plasticity of the bony carotid canal and its clinical use for assessing negative remodeling of the internal carotid artery

BACKGROUND AND OBJECTIVE: It has long been believed that the bony carotid canal has no plasticity and that a small canal represents a hypoplastic internal carotid artery. We aimed to show whether the carotid canal can narrow according to morphological changes in the internal carotid artery. MATERIAL...

Descripción completa

Detalles Bibliográficos
Autores principales: Oichi, Yuki, Mineharu, Yohei, Agawa, Yuji, Morimoto, Takaaki, Funaki, Takeshi, Fushimi, Yasutaka, Yoshida, Kazumichi, Kataoka, Hiroharu, Miyamoto, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673643/
https://www.ncbi.nlm.nih.gov/pubmed/34910773
http://dx.doi.org/10.1371/journal.pone.0261235
_version_ 1784615491946414080
author Oichi, Yuki
Mineharu, Yohei
Agawa, Yuji
Morimoto, Takaaki
Funaki, Takeshi
Fushimi, Yasutaka
Yoshida, Kazumichi
Kataoka, Hiroharu
Miyamoto, Susumu
author_facet Oichi, Yuki
Mineharu, Yohei
Agawa, Yuji
Morimoto, Takaaki
Funaki, Takeshi
Fushimi, Yasutaka
Yoshida, Kazumichi
Kataoka, Hiroharu
Miyamoto, Susumu
author_sort Oichi, Yuki
collection PubMed
description BACKGROUND AND OBJECTIVE: It has long been believed that the bony carotid canal has no plasticity and that a small canal represents a hypoplastic internal carotid artery. We aimed to show whether the carotid canal can narrow according to morphological changes in the internal carotid artery. MATERIALS AND METHODS: The carotid canal diameter was longitudinally measured in seven individuals who underwent carotid artery ligation. As moyamoya disease is known to be associated with negative remodeling of the internal carotid artery, the carotid canal diameter was measured in 106 patients with moyamoya disease, and an association with the outer diameter of the internal carotid artery or a correlation with the disease stage was investigated. The carotid canal was measured by computed tomography (106 patients), and the outer diameter of the artery was measured by high-resolution magnetic resonance imaging (63 patients). The carotid canal area was calculated by the product of the maximum axial diameter and its perpendicular diameter. RESULTS: All seven patients who underwent carotid artery ligation showed narrowing of the carotid canal, and the carotid canal area decreased by 12.2%–28.9% during a mean follow-up period of 4.2 years. In patients with moyamoya disease, the carotid canal area showed a linear correlation with the outer area of the internal carotid artery (r = 0.657, p < 0.001), and a negative correlation with the disease stage (ρ = −0.283, p < 0.001). CONCLUSION: The bony carotid canal has plasticity, and its area reflects the outer area of the internal carotid artery, therefore, it can be used to assess the remodeling of the carotid artery. A narrow carotid canal may not necessarily indicate hypoplastic internal carotid artery.
format Online
Article
Text
id pubmed-8673643
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-86736432021-12-16 Plasticity of the bony carotid canal and its clinical use for assessing negative remodeling of the internal carotid artery Oichi, Yuki Mineharu, Yohei Agawa, Yuji Morimoto, Takaaki Funaki, Takeshi Fushimi, Yasutaka Yoshida, Kazumichi Kataoka, Hiroharu Miyamoto, Susumu PLoS One Research Article BACKGROUND AND OBJECTIVE: It has long been believed that the bony carotid canal has no plasticity and that a small canal represents a hypoplastic internal carotid artery. We aimed to show whether the carotid canal can narrow according to morphological changes in the internal carotid artery. MATERIALS AND METHODS: The carotid canal diameter was longitudinally measured in seven individuals who underwent carotid artery ligation. As moyamoya disease is known to be associated with negative remodeling of the internal carotid artery, the carotid canal diameter was measured in 106 patients with moyamoya disease, and an association with the outer diameter of the internal carotid artery or a correlation with the disease stage was investigated. The carotid canal was measured by computed tomography (106 patients), and the outer diameter of the artery was measured by high-resolution magnetic resonance imaging (63 patients). The carotid canal area was calculated by the product of the maximum axial diameter and its perpendicular diameter. RESULTS: All seven patients who underwent carotid artery ligation showed narrowing of the carotid canal, and the carotid canal area decreased by 12.2%–28.9% during a mean follow-up period of 4.2 years. In patients with moyamoya disease, the carotid canal area showed a linear correlation with the outer area of the internal carotid artery (r = 0.657, p < 0.001), and a negative correlation with the disease stage (ρ = −0.283, p < 0.001). CONCLUSION: The bony carotid canal has plasticity, and its area reflects the outer area of the internal carotid artery, therefore, it can be used to assess the remodeling of the carotid artery. A narrow carotid canal may not necessarily indicate hypoplastic internal carotid artery. Public Library of Science 2021-12-15 /pmc/articles/PMC8673643/ /pubmed/34910773 http://dx.doi.org/10.1371/journal.pone.0261235 Text en © 2021 Oichi et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Oichi, Yuki
Mineharu, Yohei
Agawa, Yuji
Morimoto, Takaaki
Funaki, Takeshi
Fushimi, Yasutaka
Yoshida, Kazumichi
Kataoka, Hiroharu
Miyamoto, Susumu
Plasticity of the bony carotid canal and its clinical use for assessing negative remodeling of the internal carotid artery
title Plasticity of the bony carotid canal and its clinical use for assessing negative remodeling of the internal carotid artery
title_full Plasticity of the bony carotid canal and its clinical use for assessing negative remodeling of the internal carotid artery
title_fullStr Plasticity of the bony carotid canal and its clinical use for assessing negative remodeling of the internal carotid artery
title_full_unstemmed Plasticity of the bony carotid canal and its clinical use for assessing negative remodeling of the internal carotid artery
title_short Plasticity of the bony carotid canal and its clinical use for assessing negative remodeling of the internal carotid artery
title_sort plasticity of the bony carotid canal and its clinical use for assessing negative remodeling of the internal carotid artery
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673643/
https://www.ncbi.nlm.nih.gov/pubmed/34910773
http://dx.doi.org/10.1371/journal.pone.0261235
work_keys_str_mv AT oichiyuki plasticityofthebonycarotidcanalanditsclinicaluseforassessingnegativeremodelingoftheinternalcarotidartery
AT mineharuyohei plasticityofthebonycarotidcanalanditsclinicaluseforassessingnegativeremodelingoftheinternalcarotidartery
AT agawayuji plasticityofthebonycarotidcanalanditsclinicaluseforassessingnegativeremodelingoftheinternalcarotidartery
AT morimototakaaki plasticityofthebonycarotidcanalanditsclinicaluseforassessingnegativeremodelingoftheinternalcarotidartery
AT funakitakeshi plasticityofthebonycarotidcanalanditsclinicaluseforassessingnegativeremodelingoftheinternalcarotidartery
AT fushimiyasutaka plasticityofthebonycarotidcanalanditsclinicaluseforassessingnegativeremodelingoftheinternalcarotidartery
AT yoshidakazumichi plasticityofthebonycarotidcanalanditsclinicaluseforassessingnegativeremodelingoftheinternalcarotidartery
AT kataokahiroharu plasticityofthebonycarotidcanalanditsclinicaluseforassessingnegativeremodelingoftheinternalcarotidartery
AT miyamotosusumu plasticityofthebonycarotidcanalanditsclinicaluseforassessingnegativeremodelingoftheinternalcarotidartery