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The Schistosoma mansoni nuclear receptor FTZ-F1 maintains esophageal gland function via transcriptional regulation of meg-8.3
Schistosomes infect over 200 million of the world’s poorest people, but unfortunately treatment relies on a single drug. Nuclear hormone receptors are ligand-activated transcription factors that regulate diverse processes in metazoans, yet few have been functionally characterized in schistosomes. Du...
Autores principales: | Romero, Aracely A., Cobb, Sarah A., Collins, Julie N. R., Kliewer, Steven A., Mangelsdorf, David J., Collins, James J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673669/ https://www.ncbi.nlm.nih.gov/pubmed/34910770 http://dx.doi.org/10.1371/journal.ppat.1010140 |
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