Intrauteriner Fruchttod bei massiver SARS-CoV-2-assoziierter („severe acute respiratory syndrome coronavirus 2“) plazentarer maternaler Malperfusion im Rahmen einer SARS-CoV-2-Plazentitis

We report a case of a placenta with extensive maternal vascular malperfusion and chronic histiocytic intervillositis corresponding to SARS-CoV‑2 placentitis in the context of fetal demise at 31 weeks of gestation. Placental swamp and PCR of the placental parenchyma, umbilical cord and amnion–chorion...

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Autores principales: Eich, Marie-Lisa, Menter, Thomas, Mokwa, Nils Fabian, Grüttner, Berthold, Müller, Annette M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Medizin 2021
Materias:
Kasuistiken
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673691/
https://www.ncbi.nlm.nih.gov/pubmed/34913103
http://dx.doi.org/10.1007/s00292-021-01035-3
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author Eich, Marie-Lisa
Menter, Thomas
Mokwa, Nils Fabian
Grüttner, Berthold
Müller, Annette M.
author_facet Eich, Marie-Lisa
Menter, Thomas
Mokwa, Nils Fabian
Grüttner, Berthold
Müller, Annette M.
author_sort Eich, Marie-Lisa
collection PubMed
description We report a case of a placenta with extensive maternal vascular malperfusion and chronic histiocytic intervillositis corresponding to SARS-CoV‑2 placentitis in the context of fetal demise at 31 weeks of gestation. Placental swamp and PCR of the placental parenchyma, umbilical cord and amnion–chorion membrane showed SARS-CoV-2- and B‑betacoronavirus-specific RNA. Maternal vascular malperfusion has been described in cases of SARS-CoV‑2 infection; however, the manifested severity of this case in the setting of a severe SARS-CoV‑2 placentitis is rare. It emphasizes the need of a maternal prophylactic anticoagulation.
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spelling pubmed-86736912021-12-16 Intrauteriner Fruchttod bei massiver SARS-CoV-2-assoziierter („severe acute respiratory syndrome coronavirus 2“) plazentarer maternaler Malperfusion im Rahmen einer SARS-CoV-2-Plazentitis Eich, Marie-Lisa Menter, Thomas Mokwa, Nils Fabian Grüttner, Berthold Müller, Annette M. Pathologe Kasuistiken We report a case of a placenta with extensive maternal vascular malperfusion and chronic histiocytic intervillositis corresponding to SARS-CoV‑2 placentitis in the context of fetal demise at 31 weeks of gestation. Placental swamp and PCR of the placental parenchyma, umbilical cord and amnion–chorion membrane showed SARS-CoV-2- and B‑betacoronavirus-specific RNA. Maternal vascular malperfusion has been described in cases of SARS-CoV‑2 infection; however, the manifested severity of this case in the setting of a severe SARS-CoV‑2 placentitis is rare. It emphasizes the need of a maternal prophylactic anticoagulation. Springer Medizin 2021-12-15 2022 /pmc/articles/PMC8673691/ /pubmed/34913103 http://dx.doi.org/10.1007/s00292-021-01035-3 Text en © The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Kasuistiken
Eich, Marie-Lisa
Menter, Thomas
Mokwa, Nils Fabian
Grüttner, Berthold
Müller, Annette M.
Intrauteriner Fruchttod bei massiver SARS-CoV-2-assoziierter („severe acute respiratory syndrome coronavirus 2“) plazentarer maternaler Malperfusion im Rahmen einer SARS-CoV-2-Plazentitis
title Intrauteriner Fruchttod bei massiver SARS-CoV-2-assoziierter („severe acute respiratory syndrome coronavirus 2“) plazentarer maternaler Malperfusion im Rahmen einer SARS-CoV-2-Plazentitis
title_full Intrauteriner Fruchttod bei massiver SARS-CoV-2-assoziierter („severe acute respiratory syndrome coronavirus 2“) plazentarer maternaler Malperfusion im Rahmen einer SARS-CoV-2-Plazentitis
title_fullStr Intrauteriner Fruchttod bei massiver SARS-CoV-2-assoziierter („severe acute respiratory syndrome coronavirus 2“) plazentarer maternaler Malperfusion im Rahmen einer SARS-CoV-2-Plazentitis
title_full_unstemmed Intrauteriner Fruchttod bei massiver SARS-CoV-2-assoziierter („severe acute respiratory syndrome coronavirus 2“) plazentarer maternaler Malperfusion im Rahmen einer SARS-CoV-2-Plazentitis
title_short Intrauteriner Fruchttod bei massiver SARS-CoV-2-assoziierter („severe acute respiratory syndrome coronavirus 2“) plazentarer maternaler Malperfusion im Rahmen einer SARS-CoV-2-Plazentitis
title_sort intrauteriner fruchttod bei massiver sars-cov-2-assoziierter („severe acute respiratory syndrome coronavirus 2“) plazentarer maternaler malperfusion im rahmen einer sars-cov-2-plazentitis
topic Kasuistiken
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673691/
https://www.ncbi.nlm.nih.gov/pubmed/34913103
http://dx.doi.org/10.1007/s00292-021-01035-3
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