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Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern

Emerging variants of concern for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can transmit more efficiently and partially evade protective immune responses, thus necessitating continued refinement of antibody therapies and immunogen design. Here, we elucidate the structural basis...

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Detalles Bibliográficos
Autores principales: Li, Wenwei, Chen, Yaozong, Prévost, Jérémie, Ullah, Irfan, Lu, Maolin, Gong, Shang Yu, Tauzin, Alexandra, Gasser, Romain, Vézina, Dani, Anand, Sai Priya, Goyette, Guillaume, Chaterjee, Debashree, Ding, Shilei, Tolbert, William D., Grunst, Michael W., Bo, Yuxia, Zhang, Shijian, Richard, Jonathan, Zhou, Fei, Huang, Rick K., Esser, Lothar, Zeher, Allison, Côté, Marceline, Kumar, Priti, Sodroski, Joseph, Xia, Di, Uchil, Pradeep D., Pazgier, Marzena, Finzi, Andrés, Mothes, Walther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673750/
https://www.ncbi.nlm.nih.gov/pubmed/34971573
http://dx.doi.org/10.1016/j.celrep.2021.110210