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A critical analysis of SARS-CoV-2 (COVID-19) complexities, emerging variants, and therapeutic interventions and vaccination strategies
Coronavirus is a family of viruses that can cause diseases such as the common cold, severe acute respiratory syndrome (SARS), and Middle East respiratory syndrome (MERS). The universal outbreak of coronavirus disease 2019 (COVID-19) caused by SARS coronaviruses 2 (SARS-CoV-2) has become a global pan...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier Masson SAS.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673752/ https://www.ncbi.nlm.nih.gov/pubmed/34959116 http://dx.doi.org/10.1016/j.biopha.2021.112550 |
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author | Li, Chang-Xing Noreen, Sobia Zhang, Li-Xue Saeed, Muhammad Wu, Pei-Feng Ijaz, Muhammad Dai, Dong-Fang Maqbool, Irsah Madni, Asadullah Akram, Faizan Naveed, Muhammad Li, Jian-Hua |
author_facet | Li, Chang-Xing Noreen, Sobia Zhang, Li-Xue Saeed, Muhammad Wu, Pei-Feng Ijaz, Muhammad Dai, Dong-Fang Maqbool, Irsah Madni, Asadullah Akram, Faizan Naveed, Muhammad Li, Jian-Hua |
author_sort | Li, Chang-Xing |
collection | PubMed |
description | Coronavirus is a family of viruses that can cause diseases such as the common cold, severe acute respiratory syndrome (SARS), and Middle East respiratory syndrome (MERS). The universal outbreak of coronavirus disease 2019 (COVID-19) caused by SARS coronaviruses 2 (SARS-CoV-2) has become a global pandemic. The β-Coronaviruses, which caused SARS-CoV-2 (COVID-19), have spread in more than 213 countries, infected over 81 million people, and caused more than 1.79 million deaths. COVID-19 symptoms vary from mild fever, flu to severe pneumonia in severely ill patients. Difficult breathing, acute respiratory distress syndrome (ARDS), acute kidney disease, liver damage, and multi-organ failure ultimately lead to death. Researchers are working on different pre-clinical and clinical trials to prevent this deadly pandemic by developing new vaccines. Along with vaccines, therapeutic intervention is an integral part of healthcare response to address the ongoing threat posed by COVID-19. Despite the global efforts to understand and fight against COVID-19, many challenges need to be addressed. This article summarizes the current pandemic, different strains of SARS-CoV-2, etiology, complexities, surviving medications of COVID-19, and so far, vaccination for the treatment of COVID-19. |
format | Online Article Text |
id | pubmed-8673752 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | The Author(s). Published by Elsevier Masson SAS. |
record_format | MEDLINE/PubMed |
spelling | pubmed-86737522021-12-16 A critical analysis of SARS-CoV-2 (COVID-19) complexities, emerging variants, and therapeutic interventions and vaccination strategies Li, Chang-Xing Noreen, Sobia Zhang, Li-Xue Saeed, Muhammad Wu, Pei-Feng Ijaz, Muhammad Dai, Dong-Fang Maqbool, Irsah Madni, Asadullah Akram, Faizan Naveed, Muhammad Li, Jian-Hua Biomed Pharmacother Review Coronavirus is a family of viruses that can cause diseases such as the common cold, severe acute respiratory syndrome (SARS), and Middle East respiratory syndrome (MERS). The universal outbreak of coronavirus disease 2019 (COVID-19) caused by SARS coronaviruses 2 (SARS-CoV-2) has become a global pandemic. The β-Coronaviruses, which caused SARS-CoV-2 (COVID-19), have spread in more than 213 countries, infected over 81 million people, and caused more than 1.79 million deaths. COVID-19 symptoms vary from mild fever, flu to severe pneumonia in severely ill patients. Difficult breathing, acute respiratory distress syndrome (ARDS), acute kidney disease, liver damage, and multi-organ failure ultimately lead to death. Researchers are working on different pre-clinical and clinical trials to prevent this deadly pandemic by developing new vaccines. Along with vaccines, therapeutic intervention is an integral part of healthcare response to address the ongoing threat posed by COVID-19. Despite the global efforts to understand and fight against COVID-19, many challenges need to be addressed. This article summarizes the current pandemic, different strains of SARS-CoV-2, etiology, complexities, surviving medications of COVID-19, and so far, vaccination for the treatment of COVID-19. The Author(s). Published by Elsevier Masson SAS. 2022-02 2021-12-15 /pmc/articles/PMC8673752/ /pubmed/34959116 http://dx.doi.org/10.1016/j.biopha.2021.112550 Text en © 2021 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Review Li, Chang-Xing Noreen, Sobia Zhang, Li-Xue Saeed, Muhammad Wu, Pei-Feng Ijaz, Muhammad Dai, Dong-Fang Maqbool, Irsah Madni, Asadullah Akram, Faizan Naveed, Muhammad Li, Jian-Hua A critical analysis of SARS-CoV-2 (COVID-19) complexities, emerging variants, and therapeutic interventions and vaccination strategies |
title | A critical analysis of SARS-CoV-2 (COVID-19) complexities, emerging variants, and therapeutic interventions and vaccination strategies |
title_full | A critical analysis of SARS-CoV-2 (COVID-19) complexities, emerging variants, and therapeutic interventions and vaccination strategies |
title_fullStr | A critical analysis of SARS-CoV-2 (COVID-19) complexities, emerging variants, and therapeutic interventions and vaccination strategies |
title_full_unstemmed | A critical analysis of SARS-CoV-2 (COVID-19) complexities, emerging variants, and therapeutic interventions and vaccination strategies |
title_short | A critical analysis of SARS-CoV-2 (COVID-19) complexities, emerging variants, and therapeutic interventions and vaccination strategies |
title_sort | critical analysis of sars-cov-2 (covid-19) complexities, emerging variants, and therapeutic interventions and vaccination strategies |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673752/ https://www.ncbi.nlm.nih.gov/pubmed/34959116 http://dx.doi.org/10.1016/j.biopha.2021.112550 |
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