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Proportion of hematological cancer patients with SARS-CoV-2 infection during the COVID-19 pandemic: A systematic review and meta-analysis

INTRODUCTION: The coronavirus disease-2019 (COVID-19) has emerged as a novel infection which has spread rapidly across the globe and currently presents a grave threat to the health of the cancer patient. OBJECTIVE: The aim of this meta-analysis was to evaluate the proportion of hematological cancer...

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Autores principales: Jafari, Mohammadali, Dastgheib, Seyed Alireza, Ferdosian, Farzad, Mirjalili, Hamid, Aarafi, Hossein, Noorishadkam, Mahmood, Mazaheri, Mahta, Neamatzadeh, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Hematologia e Hemoterapia 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673822/
https://www.ncbi.nlm.nih.gov/pubmed/34931178
http://dx.doi.org/10.1016/j.htct.2021.09.020
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author Jafari, Mohammadali
Dastgheib, Seyed Alireza
Ferdosian, Farzad
Mirjalili, Hamid
Aarafi, Hossein
Noorishadkam, Mahmood
Mazaheri, Mahta
Neamatzadeh, Hossein
author_facet Jafari, Mohammadali
Dastgheib, Seyed Alireza
Ferdosian, Farzad
Mirjalili, Hamid
Aarafi, Hossein
Noorishadkam, Mahmood
Mazaheri, Mahta
Neamatzadeh, Hossein
author_sort Jafari, Mohammadali
collection PubMed
description INTRODUCTION: The coronavirus disease-2019 (COVID-19) has emerged as a novel infection which has spread rapidly across the globe and currently presents a grave threat to the health of the cancer patient. OBJECTIVE: The aim of this meta-analysis was to evaluate the proportion of hematological cancer patients with the SARS-CoV-2 infection during the COVID-19 pandemic. METHOD: A comprehensive literature review was performed on PubMed, Web of Science, Scopus, EKB SciELO, SID, CNKI and Wanfang databases to retrieve all relevant publications up to January 31, 2021. Observational studies, consecutive case-series and case-control studies were included. The proportion for hematological cancer patients with COVID-19 was estimated using the odds ratios (ORs) and 95% confidence interval (95% CIs). RESULTS: Fourteen studies with a total of 3,770 infected cancer patients and 685 hematological cancer cases with COVID-19 were selected. Combined data revealed that the overall proportion of hematological cancer patients with COVID-19 was 16.5% (95% CI 0.130 - 0.208, p ≤ 0.001). The stratified analysis by ethnicity showed that the proportion was 18.8% and 12.4% in Caucasian and Asian hematological cancer patients with COVID-19, respectively. Moreover, subgroup analysis by country of origin showed that its proportion was the highest in the United Kingdom (22.5%), followed by France (17.1%) and China (8.2%). CONCLUSION: This meta-analysis result indicated that the proportion of hematological cancer patients with SARS-CoV-2 infection during the COVID-19 pandemic was 16.5%. Further larger sample sizes and multicenter studies among different ethnic groups are necessary to get a better assessment of the proportion.
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spelling pubmed-86738222021-12-16 Proportion of hematological cancer patients with SARS-CoV-2 infection during the COVID-19 pandemic: A systematic review and meta-analysis Jafari, Mohammadali Dastgheib, Seyed Alireza Ferdosian, Farzad Mirjalili, Hamid Aarafi, Hossein Noorishadkam, Mahmood Mazaheri, Mahta Neamatzadeh, Hossein Hematol Transfus Cell Ther Review Article INTRODUCTION: The coronavirus disease-2019 (COVID-19) has emerged as a novel infection which has spread rapidly across the globe and currently presents a grave threat to the health of the cancer patient. OBJECTIVE: The aim of this meta-analysis was to evaluate the proportion of hematological cancer patients with the SARS-CoV-2 infection during the COVID-19 pandemic. METHOD: A comprehensive literature review was performed on PubMed, Web of Science, Scopus, EKB SciELO, SID, CNKI and Wanfang databases to retrieve all relevant publications up to January 31, 2021. Observational studies, consecutive case-series and case-control studies were included. The proportion for hematological cancer patients with COVID-19 was estimated using the odds ratios (ORs) and 95% confidence interval (95% CIs). RESULTS: Fourteen studies with a total of 3,770 infected cancer patients and 685 hematological cancer cases with COVID-19 were selected. Combined data revealed that the overall proportion of hematological cancer patients with COVID-19 was 16.5% (95% CI 0.130 - 0.208, p ≤ 0.001). The stratified analysis by ethnicity showed that the proportion was 18.8% and 12.4% in Caucasian and Asian hematological cancer patients with COVID-19, respectively. Moreover, subgroup analysis by country of origin showed that its proportion was the highest in the United Kingdom (22.5%), followed by France (17.1%) and China (8.2%). CONCLUSION: This meta-analysis result indicated that the proportion of hematological cancer patients with SARS-CoV-2 infection during the COVID-19 pandemic was 16.5%. Further larger sample sizes and multicenter studies among different ethnic groups are necessary to get a better assessment of the proportion. Sociedade Brasileira de Hematologia e Hemoterapia 2022 2021-12-15 /pmc/articles/PMC8673822/ /pubmed/34931178 http://dx.doi.org/10.1016/j.htct.2021.09.020 Text en © 2021 Published by Elsevier España, S.L.U. on behalf of Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Jafari, Mohammadali
Dastgheib, Seyed Alireza
Ferdosian, Farzad
Mirjalili, Hamid
Aarafi, Hossein
Noorishadkam, Mahmood
Mazaheri, Mahta
Neamatzadeh, Hossein
Proportion of hematological cancer patients with SARS-CoV-2 infection during the COVID-19 pandemic: A systematic review and meta-analysis
title Proportion of hematological cancer patients with SARS-CoV-2 infection during the COVID-19 pandemic: A systematic review and meta-analysis
title_full Proportion of hematological cancer patients with SARS-CoV-2 infection during the COVID-19 pandemic: A systematic review and meta-analysis
title_fullStr Proportion of hematological cancer patients with SARS-CoV-2 infection during the COVID-19 pandemic: A systematic review and meta-analysis
title_full_unstemmed Proportion of hematological cancer patients with SARS-CoV-2 infection during the COVID-19 pandemic: A systematic review and meta-analysis
title_short Proportion of hematological cancer patients with SARS-CoV-2 infection during the COVID-19 pandemic: A systematic review and meta-analysis
title_sort proportion of hematological cancer patients with sars-cov-2 infection during the covid-19 pandemic: a systematic review and meta-analysis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673822/
https://www.ncbi.nlm.nih.gov/pubmed/34931178
http://dx.doi.org/10.1016/j.htct.2021.09.020
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