A Phase 2 Trial of the Effect of Antiandrogen Therapy on COVID-19 Outcome: No Evidence of Benefit, Supported by Epidemiology and In Vitro Data

BACKGROUND: Men are more severely affected by COVID-19. Testosterone may influence SARS-CoV-2 infection and the immune response. OBJECTIVE: To clinically, epidemiologically, and experimentally evaluate the effect of antiandrogens on SARS-CoV-2 infection. DESIGNS, SETTINGS, AND PARTICIPANTS: A random...

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Detalles Bibliográficos
Autores principales: Welén, Karin, Rosendal, Ebba, Gisslén, Magnus, Lenman, Annasara, Freyhult, Eva, Fonseca-Rodríguez, Osvaldo, Bremell, Daniel, Stranne, Johan, Balkhed, Åse Östholm, Niward, Katarina, Repo, Johanna, Robinsson, David, Henningsson, Anna J., Styrke, Johan, Angelin, Martin, Lindquist, Elisabeth, Allard, Annika, Becker, Miriam, Rudolfsson, Stina, Buckland, Robert, Carlsson, Camilla Thellenberg, Bjartell, Anders, Nilsson, Anna C., Ahlm, Clas, Connolly, Anne-Marie Fors, Överby, Anna K., Josefsson, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. on behalf of European Association of Urology. 2022
Materias:
Prostate Cancer – Editor’s Choice
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673828/
https://www.ncbi.nlm.nih.gov/pubmed/34980495
http://dx.doi.org/10.1016/j.eururo.2021.12.013

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