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MCPH1 inhibits Condensin II during interphase by regulating its SMC2-Kleisin interface

Dramatic change in chromosomal DNA morphology between interphase and mitosis is a defining features of the eukaryotic cell cycle. Two types of enzymes, namely cohesin and condensin confer the topology of chromosomal DNA by extruding DNA loops. While condensin normally configures chromosomes exclusiv...

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Detalles Bibliográficos
Autores principales:	Houlard, Martin, Cutts, Erin E, Shamim, Muhammad S, Godwin, Jonathan, Weisz, David, Presser Aiden, Aviva, Lieberman Aiden, Erez, Schermelleh, Lothar, Vannini, Alessandro, Nasmyth, Kim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673838/ https://www.ncbi.nlm.nih.gov/pubmed/34850681 http://dx.doi.org/10.7554/eLife.73348

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