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A Modified Technique in Applying Sponge Soaked with Mitomycin C in Trabeculectomy

Trabeculectomy with adjunctive use of Mitomycin C (MMC) has been a benchmark for glaucoma filtration surgery for decades. However, there are many variations in the ways that the sponges soaked with MMC are applied during the trabeculectomy surgery. We herein describe our way of placing the MMC-soake...

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Autores principales: Zhang, Xiulan, Song, Yunhe, Liebmann, Jeffery, Weinreb, Robert N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673849/
https://www.ncbi.nlm.nih.gov/pubmed/34608066
http://dx.doi.org/10.1097/APO.0000000000000438
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author Zhang, Xiulan
Song, Yunhe
Liebmann, Jeffery
Weinreb, Robert N.
author_facet Zhang, Xiulan
Song, Yunhe
Liebmann, Jeffery
Weinreb, Robert N.
author_sort Zhang, Xiulan
collection PubMed
description Trabeculectomy with adjunctive use of Mitomycin C (MMC) has been a benchmark for glaucoma filtration surgery for decades. However, there are many variations in the ways that the sponges soaked with MMC are applied during the trabeculectomy surgery. We herein describe our way of placing the MMC-soaked sponges to improve the safety and efficacy of the trabeculectomy. The sponges are placed vertically and posteriorly with the long side of the sponge perpendicular to the limbus, not parallel. This will reduce the size of the conjunctival wound at the limbus to preserve more virgin conjunctiva that can be used for repeated trabeculectomy when needed. This will also facilitate a more posteriorly directed flow of aqueous drainage that, in turn, may increase the success rate of the trabeculectomy. We have obtained encouraging results in our practice, and further large-scale randomized studies seem warranted.
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spelling pubmed-86738492021-12-23 A Modified Technique in Applying Sponge Soaked with Mitomycin C in Trabeculectomy Zhang, Xiulan Song, Yunhe Liebmann, Jeffery Weinreb, Robert N. Asia Pac J Ophthalmol (Phila) Perspectives Trabeculectomy with adjunctive use of Mitomycin C (MMC) has been a benchmark for glaucoma filtration surgery for decades. However, there are many variations in the ways that the sponges soaked with MMC are applied during the trabeculectomy surgery. We herein describe our way of placing the MMC-soaked sponges to improve the safety and efficacy of the trabeculectomy. The sponges are placed vertically and posteriorly with the long side of the sponge perpendicular to the limbus, not parallel. This will reduce the size of the conjunctival wound at the limbus to preserve more virgin conjunctiva that can be used for repeated trabeculectomy when needed. This will also facilitate a more posteriorly directed flow of aqueous drainage that, in turn, may increase the success rate of the trabeculectomy. We have obtained encouraging results in our practice, and further large-scale randomized studies seem warranted. Lippincott Williams & Wilkins 2021-10-01 /pmc/articles/PMC8673849/ /pubmed/34608066 http://dx.doi.org/10.1097/APO.0000000000000438 Text en Copyright © 2021 Asia-Pacific Academy of Ophthalmology. Published by Wolters Kluwer Health, Inc. on behalf of the Asia-Pacific Academy of Ophthalmology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Perspectives
Zhang, Xiulan
Song, Yunhe
Liebmann, Jeffery
Weinreb, Robert N.
A Modified Technique in Applying Sponge Soaked with Mitomycin C in Trabeculectomy
title A Modified Technique in Applying Sponge Soaked with Mitomycin C in Trabeculectomy
title_full A Modified Technique in Applying Sponge Soaked with Mitomycin C in Trabeculectomy
title_fullStr A Modified Technique in Applying Sponge Soaked with Mitomycin C in Trabeculectomy
title_full_unstemmed A Modified Technique in Applying Sponge Soaked with Mitomycin C in Trabeculectomy
title_short A Modified Technique in Applying Sponge Soaked with Mitomycin C in Trabeculectomy
title_sort modified technique in applying sponge soaked with mitomycin c in trabeculectomy
topic Perspectives
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8673849/
https://www.ncbi.nlm.nih.gov/pubmed/34608066
http://dx.doi.org/10.1097/APO.0000000000000438
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