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Tert-Butylhydroquinone Prevents Oxidative Stress-Mediated Apoptosis and Extracellular Matrix Degradation in Rat Chondrocytes

Oxidative stress-induced chondrocyte apoptosis and degradation of the extracellular matrix (ECM) play an important role in the progression of osteoarthritis (OA). In addition, tert-butylhydroquinone (TBHQ) is an activator of the nuclear factor erythroid derived-2-related factor 2 (Nrf2). The present...

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Detalles Bibliográficos
Autores principales: Yang, Bo, Huang, Haisheng, He, Qisong, Lu, Wei, Zheng, Lu, Cui, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674040/
https://www.ncbi.nlm.nih.gov/pubmed/34925524
http://dx.doi.org/10.1155/2021/1905995