Cargando…

hZIP1 Inhibits Progression of Clear Cell Renal Cell Carcinoma by Suppressing NF-kB/HIF-1α Pathway

PURPOSE: Accumulating literature has suggested that hZIP1 and HIF-1α play vital roles in the tumor process of clear cell renal cell carcinoma (ccRCC). However, the functional roles of hZIP1 and HIF-1α in ccRCC remain largely unknown. METHODS: HIF-1α protein level was evaluated by a western blot in c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhan, Bo, Dong, Xiao, Yuan, Yulin, Gong, Zheng, Li, Bohan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674186/ https://www.ncbi.nlm.nih.gov/pubmed/34926261 http://dx.doi.org/10.3389/fonc.2021.759818

Ejemplares similares

FBXO30 functions as a tumor suppressor and an E3 ubiquitin ligase for hZIP1-mediated HIF-1α degradation in renal cell carcinoma
por: Yuan, Yulin, et al.
Publicado: (2023)

hZip2 and hZip3 zinc transporters are down regulated in human prostate adenocarcinomatous glands
por: Desouki, Mohamed M, et al.
Publicado: (2007)

hZIP1 zinc uptake transporter down regulation and zinc depletion in prostate cancer
por: Franklin, Renty B, et al.
Publicado: (2005)

Persistent low expression of hZip1 in mucinous carcinomas of the ovary, colon, stomach and lung
por: Desouki, Mohamed Mokhtar, et al.
Publicado: (2015)

Hypoxia‐inducible factor (HIF)‐1α‐induced regulation of lung injury in pulmonary aspiration is mediated through NF‐kB
por: Suresh, Madathilparambil V., et al.
Publicado: (2022)

NF-kB-dependent activation of STAT3 by H. pylori is suppressed by TFF1
por: Soutto, Mohammed, et al.
Publicado: (2021)

NF-kB and the CLL microenvironment
por: O’Donnell, Alice, et al.
Publicado: (2023)

Inhibition of PTGS1 promotes osteogenic differentiation of adipose-derived stem cells by suppressing NF-kB signaling
por: Wang, Yuejun, et al.
Publicado: (2019)

Maf1 Ameliorates Sepsis-Associated Encephalopathy by Suppressing the NF-kB/NLRP3 Inflammasome Signaling Pathway
por: Chen, Shenglong, et al.
Publicado: (2020)

IκBα beyond the NF-kB dogma
por: Mulero, Maria Carmen, et al.
Publicado: (2013)

NKX6.3 Regulates Reactive Oxygen Species Production by Suppressing NF-kB and DNMT1 Activities in Gastric Epithelial Cells
por: Yoon, Jung Hwan, et al.
Publicado: (2017)

NF-kB inhibitor blocks B cell development at two checkpoints
por: Feng, Biao, et al.
Publicado: (2004)

HIF-1α Dependent Upregulation of ZIP8, ZIP14, and TRPA1 Modify Intracellular Zn(2+) Accumulation in Inflammatory Synoviocytes
por: Hatano, Noriyuki, et al.
Publicado: (2021)

Shigella flexneri suppresses NF-kB activation by inhibiting linear ubiquitin chain ligation
por: de Jong, Maarten F., et al.
Publicado: (2016)

ZNF545 suppresses human hepatocellular carcinoma growth by inhibiting NF-kB signaling
por: Yang, Weili, et al.
Publicado: (2017)

Inhibition of NF-kB 1 (NF-kBp50) by RNA interference in chicken macrophage HD11 cell line challenged with Salmonellaenteritidis
por: Chiang, Hsin-I, et al.
Publicado: (2009)

Annexin A4 fucosylation enhances its interaction with the NF-kB p50 and promotes tumor progression of ovarian clear cell carcinoma
por: Wang, Huimin, et al.
Publicado: (2016)

NF-kB Expression in IgA Nephropathy Outcome
por: Silva, G. E. B., et al.
Publicado: (2011)

NF-kB pathway is involved in microscopic colitis pathogenesis
por: Pisani, Laura Francesca, et al.
Publicado: (2022)

Predominant role of Tax sumoylation in Tax-induced NF-kB activation in T cells
por: Bonnet, Amandine, et al.
Publicado: (2011)

PUMA and NF-kB Are Cell Signaling Predictors of Reovirus Oncolysis of Breast Cancer
por: Thirukkumaran, Chandini, et al.
Publicado: (2017)

Dysregulation of NF-kB in glandular epithelial cells results in Sjögren’s-like features
por: Wang, Xiaoyan, et al.
Publicado: (2018)

Inhibitory effects of quail egg on mast cells degranulation by suppressing PAR2-mediated MAPK and NF-kB activation
por: Lianto, Priscilia, et al.
Publicado: (2018)

The RNA-binding protein QKI suppresses tumorigenesis of clear cell renal cell carcinoma by regulating the expression of HIF-1α
por: Shi, Fei, et al.
Publicado: (2020)

Lipopolysaccharide Activating NF-kB Signaling by Regulates HTRA1 Expression in Human Retinal Pigment Epithelial Cells
por: Pan, Shengliu, et al.
Publicado: (2023)

Ginsenoside F1 Ameliorates Endothelial Cell Inflammatory Injury and Prevents Atherosclerosis in Mice through A20-Mediated Suppression of NF-kB Signaling
por: Qin, Meng, et al.
Publicado: (2017)

LMO1 Plays an Oncogenic Role in Human Glioma Associated With NF-kB Pathway
por: Gao, Lei, et al.
Publicado: (2022)

Effects of HIF-1α and HIF2α on Growth and Metabolism of Clear-Cell Renal Cell Carcinoma 786-0 Xenografts
por: Biswas, Swethajit, et al.
Publicado: (2010)

Opposite prognostic roles of HIF1α and HIF2α expressions in bone metastatic clear cell renal cell cancer
por: Szendrői, Attila, et al.
Publicado: (2016)

HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice
por: Hoefflin, Rouven, et al.
Publicado: (2020)

Histone Deacetylases and NF-kB Signaling Coordinate Expression of CX3CL1 in Epithelial Cells in Response to Microbial Challenge by Suppressing miR-424 and miR-503
por: Zhou, Rui, et al.
Publicado: (2013)

2-O-Methylhonokiol Suppresses HCV Replication via TRAF6-Mediated NF-kB Activation
por: Jeong, Suyun, et al.
Publicado: (2021)

Characterization of NF-kB-mediated inhibition of catechol-O-methyltransferase
por: Tchivileva, Inna E, et al.
Publicado: (2009)

The SUMOylation machinery is dispensable for Tax-induced NF-kB activation
por: Pène, Sabrina, et al.
Publicado: (2014)

Diisononyl phthalate aggravates allergic dermatitis by activation of NF-kB
por: Kang, Jun, et al.
Publicado: (2016)

NF‐kB signaling in cardiomyocytes is inhibited by sevoflurane and promoted by propofol
por: Oda‐Kawashima, Keiko, et al.
Publicado: (2020)

The Pivotal Role of NF-kB in the Pathogenesis and Therapeutics of Alzheimer’s Disease
por: Sun, Emily, et al.
Publicado: (2022)

Coilin as a regulator of NF-kB mediated inflammation in preeclampsia
por: Logan, Madelyn K., et al.
Publicado: (2022)

Autocrine stimulation of clear-cell renal carcinoma cell migration in hypoxia via HIF-independent suppression of thrombospondin-1
por: Bienes-Martínez, Raquel, et al.
Publicado: (2012)

The up‐regulation of NDRG1 by HIF counteracts the cancer‐promoting effect of HIF in VHL‐deficient clear cell renal cell carcinoma
por: Zhang, Zheng‐Yan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_0v9fkf5tmqpheiki55qtbstrfp