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COVID-19 vaccination strategies depend on the underlying network of social interactions

Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, different mitigation and management strategies limiting economic and social activities have been implemented across many countries. Despite these strategies, the virus continues to spread and mutate. As a result, vaccinations are n...

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Autores principales: Saunders, Helena A., Schwartz, Jean-Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674282/
https://www.ncbi.nlm.nih.gov/pubmed/34912001
http://dx.doi.org/10.1038/s41598-021-03167-1
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author Saunders, Helena A.
Schwartz, Jean-Marc
author_facet Saunders, Helena A.
Schwartz, Jean-Marc
author_sort Saunders, Helena A.
collection PubMed
description Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, different mitigation and management strategies limiting economic and social activities have been implemented across many countries. Despite these strategies, the virus continues to spread and mutate. As a result, vaccinations are now administered to suppress the pandemic. Current COVID-19 epidemic models need to be expanded to account for the change in behaviour of new strains, such as an increased virulence and higher transmission rate. Furthermore, models need to account for an increasingly vaccinated population. We present a network model of COVID-19 transmission accounting for different immunity and vaccination scenarios. We conduct a parameter sensitivity analysis and find the average immunity length after an infection to be one of the most critical parameters that define the spread of the disease. Furthermore, we simulate different vaccination strategies and show that vaccinating highly connected individuals first is the quickest strategy for controlling the disease.
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spelling pubmed-86742822021-12-16 COVID-19 vaccination strategies depend on the underlying network of social interactions Saunders, Helena A. Schwartz, Jean-Marc Sci Rep Article Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, different mitigation and management strategies limiting economic and social activities have been implemented across many countries. Despite these strategies, the virus continues to spread and mutate. As a result, vaccinations are now administered to suppress the pandemic. Current COVID-19 epidemic models need to be expanded to account for the change in behaviour of new strains, such as an increased virulence and higher transmission rate. Furthermore, models need to account for an increasingly vaccinated population. We present a network model of COVID-19 transmission accounting for different immunity and vaccination scenarios. We conduct a parameter sensitivity analysis and find the average immunity length after an infection to be one of the most critical parameters that define the spread of the disease. Furthermore, we simulate different vaccination strategies and show that vaccinating highly connected individuals first is the quickest strategy for controlling the disease. Nature Publishing Group UK 2021-12-15 /pmc/articles/PMC8674282/ /pubmed/34912001 http://dx.doi.org/10.1038/s41598-021-03167-1 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Saunders, Helena A.
Schwartz, Jean-Marc
COVID-19 vaccination strategies depend on the underlying network of social interactions
title COVID-19 vaccination strategies depend on the underlying network of social interactions
title_full COVID-19 vaccination strategies depend on the underlying network of social interactions
title_fullStr COVID-19 vaccination strategies depend on the underlying network of social interactions
title_full_unstemmed COVID-19 vaccination strategies depend on the underlying network of social interactions
title_short COVID-19 vaccination strategies depend on the underlying network of social interactions
title_sort covid-19 vaccination strategies depend on the underlying network of social interactions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674282/
https://www.ncbi.nlm.nih.gov/pubmed/34912001
http://dx.doi.org/10.1038/s41598-021-03167-1
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