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A schizophrenia subgroup with elevated inflammation displays reduced microglia, increased peripheral immune cell and altered neurogenesis marker gene expression in the subependymal zone

Inflammation regulates neurogenesis, and the brains of patients with schizophrenia and bipolar disorder have reduced expression of neurogenesis markers in the subependymal zone (SEZ), the birthplace of inhibitory interneurons. Inflammation is associated with cortical interneuron deficits, but the re...

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Detalles Bibliográficos
Autores principales: North, Hayley F., Weissleder, Christin, Fullerton, Janice M., Sager, Rachel, Webster, Maree J., Weickert, Cynthia Shannon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674325/
https://www.ncbi.nlm.nih.gov/pubmed/34911938
http://dx.doi.org/10.1038/s41398-021-01742-8

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