Cargando…
A schizophrenia subgroup with elevated inflammation displays reduced microglia, increased peripheral immune cell and altered neurogenesis marker gene expression in the subependymal zone
Inflammation regulates neurogenesis, and the brains of patients with schizophrenia and bipolar disorder have reduced expression of neurogenesis markers in the subependymal zone (SEZ), the birthplace of inhibitory interneurons. Inflammation is associated with cortical interneuron deficits, but the re...
Autores principales: | North, Hayley F., Weissleder, Christin, Fullerton, Janice M., Sager, Rachel, Webster, Maree J., Weickert, Cynthia Shannon |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674325/ https://www.ncbi.nlm.nih.gov/pubmed/34911938 http://dx.doi.org/10.1038/s41398-021-01742-8 |
Ejemplares similares
-
O11.5. INCREASED INFLAMMATION AND MACROPHAGE INFILTRATION IS ASSOCIATED WITH ALTERED SUBEPENDYMAL ZONE NEUROGENESIS IN SCHIZOPHRENIA BUT NOT BIPOLAR DISORDER
por: North, Hayley, et al.
Publicado: (2020) -
Identifying gene expression profiles associated with neurogenesis and inflammation in the human subependymal zone from development through aging
por: Bitar, Mainá, et al.
Publicado: (2022) -
Reduction in IGF1 mRNA in the Human Subependymal Zone During Aging
por: Weissleder, Christin, et al.
Publicado: (2019) -
Decline in Proliferation and Immature Neuron Markers in the Human Subependymal Zone during Aging: Relationship to EGF- and FGF-Related Transcripts
por: Weissleder, Christin, et al.
Publicado: (2016) -
M174. REDUCED CHEMOKINE SIGNALLING CAPACITY IS ASSOCIATED WITH INHIBITORY INTERNEURON DYSFUNCTION IN SUBCORTICAL BRAIN REGIONS IN SCHIZOPHRENIA AND BIPOLAR DISORDER
por: Weissleder, Christin, et al.
Publicado: (2020)