Early senescence and production of senescence-associated cytokines are major determinants of radioresistance in head-and-neck squamous cell carcinoma

Resistance against radio(chemo)therapy-induced cell death is a major determinant of oncological treatment failure and remains a perpetual clinical challenge. The underlying mechanisms are manifold and demand for comprehensive, cancer entity- and subtype-specific examination. In the present study, re...

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Detalles Bibliográficos
Autores principales: Schoetz, Ulrike, Klein, Diana, Hess, Julia, Shnayien, Seyd, Spoerl, Steffen, Orth, Michael, Mutlu, Samet, Hennel, Roman, Sieber, Anja, Ganswindt, Ute, Luka, Benedikt, Thomsen, Andreas R., Unger, Kristian, Jendrossek, Verena, Zitzelsberger, Horst, Blüthgen, Nils, Belka, Claus, Unkel, Steffen, Klinger, Bertram, Lauber, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674332/
https://www.ncbi.nlm.nih.gov/pubmed/34911941
http://dx.doi.org/10.1038/s41419-021-04454-5

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