Impact of maternal antibodies and microbiota development on the immunogenicity of oral rotavirus vaccine in African, Indian, and European infants

Identifying risk factors for impaired oral rotavirus vaccine (ORV) efficacy in low-income countries may lead to improvements in vaccine design and delivery. In this prospective cohort study, we measure maternal rotavirus antibodies, environmental enteric dysfunction (EED), and bacterial gut microbio...

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Detalles Bibliográficos
Autores principales: Parker, Edward P. K., Bronowski, Christina, Sindhu, Kulandaipalayam Natarajan C., Babji, Sudhir, Benny, Blossom, Carmona-Vicente, Noelia, Chasweka, Nedson, Chinyama, End, Cunliffe, Nigel A., Dube, Queen, Giri, Sidhartha, Grassly, Nicholas C., Gunasekaran, Annai, Howarth, Deborah, Immanuel, Sushil, Jere, Khuzwayo C., Kampmann, Beate, Lowe, Jenna, Mandolo, Jonathan, Praharaj, Ira, Rani, Bakthavatsalam Sandya, Silas, Sophia, Srinivasan, Vivek Kumar, Turner, Mark, Venugopal, Srinivasan, Verghese, Valsan Philip, Darby, Alistair C., Kang, Gagandeep, Iturriza-Gómara, Miren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674366/
https://www.ncbi.nlm.nih.gov/pubmed/34911947
http://dx.doi.org/10.1038/s41467-021-27074-1

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