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Microglia Impede Oligodendrocyte Generation in Aged Brain

PURPOSE: Age-related increase in myelin loss may be responsible for brain atrophy, and the mechanism is not completely understood. We aim to comprehensively delineate oligodendrocyte heterogeneity in young and aged mice and to reveal the underlying mechanism for myelin loss during aging. METHODS: Di...

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Detalles Bibliográficos
Autores principales: Luan, Weimin, Qi, Xiqian, Liang, Feng, Zhang, Xiaotao, Jin, Ziyang, Shi, Ligen, Luo, Benyan, Dai, Xuejiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674668/
https://www.ncbi.nlm.nih.gov/pubmed/34924766
http://dx.doi.org/10.2147/JIR.S338242