Cargando…
Microglia Impede Oligodendrocyte Generation in Aged Brain
PURPOSE: Age-related increase in myelin loss may be responsible for brain atrophy, and the mechanism is not completely understood. We aim to comprehensively delineate oligodendrocyte heterogeneity in young and aged mice and to reveal the underlying mechanism for myelin loss during aging. METHODS: Di...
Autores principales: | Luan, Weimin, Qi, Xiqian, Liang, Feng, Zhang, Xiaotao, Jin, Ziyang, Shi, Ligen, Luo, Benyan, Dai, Xuejiao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674668/ https://www.ncbi.nlm.nih.gov/pubmed/34924766 http://dx.doi.org/10.2147/JIR.S338242 |
Ejemplares similares
-
Aged microglia promote peripheral T cell infiltration by reprogramming the microenvironment of neurogenic niches
por: Zhang, Xiaotao, et al.
Publicado: (2022) -
InterCellDB: A User‐Defined Database for Inferring Intercellular Networks
por: Jin, Ziyang, et al.
Publicado: (2022) -
Transforming growth factor‐beta renders ageing microglia inhibitory to oligodendrocyte generation by CNS progenitors
por: Baror, Roey, et al.
Publicado: (2019) -
A Unique Type of Highly-Activated Microglia Evoking Brain Inflammation via Mif/Cd74 Signaling Axis in Aged Mice
por: Jin, Chenghao, et al.
Publicado: (2021) -
Oligodendrocytes in the aging brain
por: Sams, Eleanor Catherine
Publicado: (2021)