Distribution of Large and Small Dorsal Root Ganglion Neurons in Common Marmosets

The aim of this study was to elucidate the size and distribution of dorsal root ganglion (DRG) neurons in non-human primates and to compare them with those of rodent DRG neurons. By measuring the size of NeuN-, NF200-, and peripherin-positive DRG neurons in the lumbar spinal cord of rats and marmose...

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Autores principales: Kudo, Moeko, Wupuer, Sidikejiang, Kubota, Shinji, Seki, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674680/
https://www.ncbi.nlm.nih.gov/pubmed/34924967
http://dx.doi.org/10.3389/fnsys.2021.801492
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author Kudo, Moeko
Wupuer, Sidikejiang
Kubota, Shinji
Seki, Kazuhiko
author_facet Kudo, Moeko
Wupuer, Sidikejiang
Kubota, Shinji
Seki, Kazuhiko
author_sort Kudo, Moeko
collection PubMed
description The aim of this study was to elucidate the size and distribution of dorsal root ganglion (DRG) neurons in non-human primates and to compare them with those of rodent DRG neurons. By measuring the size of NeuN-, NF200-, and peripherin-positive DRG neurons in the lumbar spinal cord of rats and marmosets, we found that the cell size distribution pattern was comparable in both species, although DRG neurons in marmosets were larger than those of rodents. This is the first demonstration that DRG neurons in marmosets have a bimodal size distribution, which has been well established in rodents and humans.
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spelling pubmed-86746802021-12-17 Distribution of Large and Small Dorsal Root Ganglion Neurons in Common Marmosets Kudo, Moeko Wupuer, Sidikejiang Kubota, Shinji Seki, Kazuhiko Front Syst Neurosci Neuroscience The aim of this study was to elucidate the size and distribution of dorsal root ganglion (DRG) neurons in non-human primates and to compare them with those of rodent DRG neurons. By measuring the size of NeuN-, NF200-, and peripherin-positive DRG neurons in the lumbar spinal cord of rats and marmosets, we found that the cell size distribution pattern was comparable in both species, although DRG neurons in marmosets were larger than those of rodents. This is the first demonstration that DRG neurons in marmosets have a bimodal size distribution, which has been well established in rodents and humans. Frontiers Media S.A. 2021-12-02 /pmc/articles/PMC8674680/ /pubmed/34924967 http://dx.doi.org/10.3389/fnsys.2021.801492 Text en Copyright © 2021 Kudo, Wupuer, Kubota and Seki. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Kudo, Moeko
Wupuer, Sidikejiang
Kubota, Shinji
Seki, Kazuhiko
Distribution of Large and Small Dorsal Root Ganglion Neurons in Common Marmosets
title Distribution of Large and Small Dorsal Root Ganglion Neurons in Common Marmosets
title_full Distribution of Large and Small Dorsal Root Ganglion Neurons in Common Marmosets
title_fullStr Distribution of Large and Small Dorsal Root Ganglion Neurons in Common Marmosets
title_full_unstemmed Distribution of Large and Small Dorsal Root Ganglion Neurons in Common Marmosets
title_short Distribution of Large and Small Dorsal Root Ganglion Neurons in Common Marmosets
title_sort distribution of large and small dorsal root ganglion neurons in common marmosets
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674680/
https://www.ncbi.nlm.nih.gov/pubmed/34924967
http://dx.doi.org/10.3389/fnsys.2021.801492
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