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Aggregated Mycobacterium tuberculosis Enhances the Inflammatory Response

Mycobacterium tuberculosis (Mtb) bacilli readily aggregate. We previously reported that Mtb aggregates lead to phagocyte death and subsequent efficient replication in the dead infected cells. Here, we examined the transcriptional response of human monocyte derived macrophages to phagocytosis of aggr...

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Detalles Bibliográficos
Autores principales: Rodel, Hylton E., Ferreira, Isabella A. T. M., Ziegler, Carly G. K., Ganga, Yashica, Bernstein, Mallory, Hwa, Shi-Hsia, Nargan, Kievershen, Lustig, Gila, Kaplan, Gilla, Noursadeghi, Mahdad, Shalek, Alex K., Steyn, Adrie J. C., Sigal, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674758/
https://www.ncbi.nlm.nih.gov/pubmed/34925266
http://dx.doi.org/10.3389/fmicb.2021.757134