Committed Human CD23-Negative Light-Zone Germinal Center B Cells Delineate Transcriptional Program Supporting Plasma Cell Differentiation

B cell affinity maturation occurs in the germinal center (GC). Light-zone (LZ) GC B cells (B(GC)-cells) interact with follicular dendritic cells (FDCs) and compete for the limited, sequential help from T follicular helper cells needed to escape from apoptosis and complete their differentiation. The...

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Detalles Bibliográficos
Autores principales: Santamaria, Kathleen, Desmots, Fabienne, Leonard, Simon, Caron, Gersende, Haas, Marion, Delaloy, Céline, Chatonnet, Fabrice, Rossille, Delphine, Pignarre, Amandine, Monvoisin, Céline, Seffals, Marine, Lamaison, Claire, Cogné, Michel, Tarte, Karin, Fest, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674954/
https://www.ncbi.nlm.nih.gov/pubmed/34925321
http://dx.doi.org/10.3389/fimmu.2021.744573

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