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Attenuating persistent sodium current–induced atrial myopathy and fibrillation by preventing mitochondrial oxidative stress

Mechanistically driven therapies for atrial fibrillation (AF), the most common cardiac arrhythmia, are urgently needed, the development of which requires improved understanding of the cellular signaling pathways that facilitate the structural and electrophysiological remodeling that occurs in the at...

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Detalles Bibliográficos
Autores principales: Avula, Uma Mahesh R., Dridi, Haikel, Chen, Bi-xing, Yuan, Qi, Katchman, Alexander N., Reiken, Steven R., Desai, Amar D., Parsons, Samantha, Baksh, Haajra, Ma, Elaine, Dasrat, Parmanand, Ji, Ruiping, Lin, Yejun, Sison, Christine, Lederer, W. Jonathan, Joca, Humberto C., Ward, Christopher W., Greiser, Maura, Marks, Andrew R., Marx, Steven O., Wan, Elaine Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675199/
https://www.ncbi.nlm.nih.gov/pubmed/34710060
http://dx.doi.org/10.1172/jci.insight.147371