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Attenuating persistent sodium current–induced atrial myopathy and fibrillation by preventing mitochondrial oxidative stress
Mechanistically driven therapies for atrial fibrillation (AF), the most common cardiac arrhythmia, are urgently needed, the development of which requires improved understanding of the cellular signaling pathways that facilitate the structural and electrophysiological remodeling that occurs in the at...
Autores principales: | Avula, Uma Mahesh R., Dridi, Haikel, Chen, Bi-xing, Yuan, Qi, Katchman, Alexander N., Reiken, Steven R., Desai, Amar D., Parsons, Samantha, Baksh, Haajra, Ma, Elaine, Dasrat, Parmanand, Ji, Ruiping, Lin, Yejun, Sison, Christine, Lederer, W. Jonathan, Joca, Humberto C., Ward, Christopher W., Greiser, Maura, Marks, Andrew R., Marx, Steven O., Wan, Elaine Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675199/ https://www.ncbi.nlm.nih.gov/pubmed/34710060 http://dx.doi.org/10.1172/jci.insight.147371 |
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