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NLRP3/caspase-1/GSDMD–mediated pyroptosis exerts a crucial role in astrocyte pathological injury in mouse model of depression

Emerging evidence suggests that astrocyte loss is one of the most important pathological features in the hippocampus of patients with major depressive disorder (MDD) and depressive mice. Pyroptosis is a recently discovered form of programmed cell death depending on Caspase–gasdermin D (Casp-GSDMD),...

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Detalles Bibliográficos
Autores principales:	Li, Shanshan, Sun, Yiming, Song, Mengmeng, Song, Yuting, Fang, Yinquan, Zhang, Qingyu, Li, Xueting, Song, Nanshan, Ding, Jianhua, Lu, Ming, Hu, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675200/ https://www.ncbi.nlm.nih.gov/pubmed/34877938 http://dx.doi.org/10.1172/jci.insight.146852

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