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Nuage condensates: accelerators or circuit breakers for sRNA silencing pathways?

Nuage are RNA-rich condensates that assemble around the nuclei of developing germ cells. Many proteins required for the biogenesis and function of silencing small RNAs (sRNAs) enrich in nuage, and it is often assumed that nuage is the cellular site where sRNAs are synthesized and encounter target tr...

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Detalles Bibliográficos
Autores principales: Ouyang, John Paul Tsu, Seydoux, Geraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675287/
https://www.ncbi.nlm.nih.gov/pubmed/34772788
http://dx.doi.org/10.1261/rna.079003.121

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