The ENIGMA Stroke Recovery Working Group: Big data neuroimaging to study brain–behavior relationships after stroke

The goal of the Enhancing Neuroimaging Genetics through Meta‐Analysis (ENIGMA) Stroke Recovery working group is to understand brain and behavior relationships using well‐powered meta‐ and mega‐analytic approaches. ENIGMA Stroke Recovery has data from over 2,100 stroke patients collected across 39 re...

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Detalles Bibliográficos
Autores principales: Liew, Sook‐Lei, Zavaliangos‐Petropulu, Artemis, Jahanshad, Neda, Lang, Catherine E., Hayward, Kathryn S., Lohse, Keith R., Juliano, Julia M., Assogna, Francesca, Baugh, Lee A., Bhattacharya, Anup K., Bigjahan, Bavrina, Borich, Michael R., Boyd, Lara A., Brodtmann, Amy, Buetefisch, Cathrin M., Byblow, Winston D., Cassidy, Jessica M., Conforto, Adriana B., Craddock, R. Cameron, Dimyan, Michael A., Dula, Adrienne N., Ermer, Elsa, Etherton, Mark R., Fercho, Kelene A., Gregory, Chris M., Hadidchi, Shahram, Holguin, Jess A., Hwang, Darryl H., Jung, Simon, Kautz, Steven A., Khlif, Mohamed Salah, Khoshab, Nima, Kim, Bokkyu, Kim, Hosung, Kuceyeski, Amy, Lotze, Martin, MacIntosh, Bradley J., Margetis, John L., Mohamed, Feroze B., Piras, Fabrizio, Ramos‐Murguialday, Ander, Richard, Geneviève, Roberts, Pamela, Robertson, Andrew D., Rondina, Jane M., Rost, Natalia S., Sanossian, Nerses, Schweighofer, Nicolas, Seo, Na Jin, Shiroishi, Mark S., Soekadar, Surjo R., Spalletta, Gianfranco, Stinear, Cathy M., Suri, Anisha, Tang, Wai Kwong W., Thielman, Gregory T., Vecchio, Daniela, Villringer, Arno, Ward, Nick S., Werden, Emilio, Westlye, Lars T., Winstein, Carolee, Wittenberg, George F., Wong, Kristin A., Yu, Chunshui, Cramer, Steven C., Thompson, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675421/
https://www.ncbi.nlm.nih.gov/pubmed/32310331
http://dx.doi.org/10.1002/hbm.25015
Descripción
Sumario:The goal of the Enhancing Neuroimaging Genetics through Meta‐Analysis (ENIGMA) Stroke Recovery working group is to understand brain and behavior relationships using well‐powered meta‐ and mega‐analytic approaches. ENIGMA Stroke Recovery has data from over 2,100 stroke patients collected across 39 research studies and 10 countries around the world, comprising the largest multisite retrospective stroke data collaboration to date. This article outlines the efforts taken by the ENIGMA Stroke Recovery working group to develop neuroinformatics protocols and methods to manage multisite stroke brain magnetic resonance imaging, behavioral and demographics data. Specifically, the processes for scalable data intake and preprocessing, multisite data harmonization, and large‐scale stroke lesion analysis are described, and challenges unique to this type of big data collaboration in stroke research are discussed. Finally, future directions and limitations, as well as recommendations for improved data harmonization through prospective data collection and data management, are provided.

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