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Evaluating brain structure traits as endophenotypes using polygenicity and discoverability

Human brain structure traits have been hypothesized to be broad endophenotypes for neuropsychiatric disorders, implying that brain structure traits are comparatively “closer to the underlying biology.” Genome‐wide association studies from large sample sizes allow for the comparison of common variant...

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Detalles Bibliográficos
Autores principales: Matoba, Nana, Love, Michael I., Stein, Jason L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675430/
https://www.ncbi.nlm.nih.gov/pubmed/33098356
http://dx.doi.org/10.1002/hbm.25257

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