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Evaluating brain structure traits as endophenotypes using polygenicity and discoverability
Human brain structure traits have been hypothesized to be broad endophenotypes for neuropsychiatric disorders, implying that brain structure traits are comparatively “closer to the underlying biology.” Genome‐wide association studies from large sample sizes allow for the comparison of common variant...
Autores principales: | Matoba, Nana, Love, Michael I., Stein, Jason L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675430/ https://www.ncbi.nlm.nih.gov/pubmed/33098356 http://dx.doi.org/10.1002/hbm.25257 |
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