RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site

Fragile X-related protein-1 (FXR1) gene is highly amplified in patients with ovarian cancer, and this amplification is associated with increased expression of both FXR1 mRNA and protein. FXR1 expression directly associates with the survival and proliferation of cancer cells. Surface sensing of trans...

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Detalles Bibliográficos
Autores principales: George, Jasmine, Li, Yongsheng, Kadamberi, Ishaque P., Parashar, Deepak, Tsaih, Shirng-Wern, Gupta, Prachi, Geethadevi, Anjali, Chen, Changliang, Ghosh, Chandrima, Sun, Yunguang, Mittal, Sonam, Ramchandran, Ramani, Rui, Hallgeir, Lopez-Berestein, Gabriel, Rodriguez-Aguayo, Cristian, Leone, Gustavo, Rader, Janet S., Sood, Anil K., Dey, Madhusudan, Pradeep, Sunila, Chaluvally-Raghavan, Pradeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675433/
https://www.ncbi.nlm.nih.gov/pubmed/34731628
http://dx.doi.org/10.1016/j.celrep.2021.109934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675433/
https://www.ncbi.nlm.nih.gov/pubmed/34731628
http://dx.doi.org/10.1016/j.celrep.2021.109934

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