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High efficiency closed-system gene transfer using automated spinoculation

BACKGROUND: Gene transfer is an important tool for cellular therapies. Lentiviral vectors are most effectively transferred into lymphocytes or hematopoietic progenitor cells using spinoculation. To enable cGMP (current Good Manufacturing Practice)-compliant cell therapy production, we developed and...

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Detalles Bibliográficos
Autores principales:	Remley, Victoria Ann, Jin, Jianjian, Sarkar, Sarmila, Moses, Larry, Prochazkova, Michaela, Cai, Yihua, Shao, Lipei, Liu, Hui, Fuksenko, Tatyana, Jin, Ping, Stroncek, David F., Highfill, Steven L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675485/ https://www.ncbi.nlm.nih.gov/pubmed/34819105 http://dx.doi.org/10.1186/s12967-021-03126-4

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