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Optimized Lockdown Strategies for Curbing the Spread of COVID-19: A South African Case Study

To curb the spread of COVID-19, many governments around the world have implemented tiered lockdowns with varying degrees of stringency. Lockdown levels are typically increased when the disease spreads and reduced when the disease abates. A predictive control approach is used to develop optimized loc...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IEEE 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675548/
https://www.ncbi.nlm.nih.gov/pubmed/34976564
http://dx.doi.org/10.1109/ACCESS.2020.3037415
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description To curb the spread of COVID-19, many governments around the world have implemented tiered lockdowns with varying degrees of stringency. Lockdown levels are typically increased when the disease spreads and reduced when the disease abates. A predictive control approach is used to develop optimized lockdown strategies for curbing the spread of COVID-19. The strategies are then applied to South African data. The South African case is of interest as the South African government has defined five distinct levels of lockdown, which serves as a discrete control input. An epidemiological model for the spread of COVID-19 in South Africa was previously developed, and is used in conjunction with a hybrid model predictive controller to optimize lockdown management under different policy scenarios. Scenarios considered include how to flatten the curve to a level that the healthcare system can cope with, how to balance lives and livelihoods, and what impact the compliance of the population to the lockdown measures has on the spread of COVID-19. The main purpose of this article is to show what the optimal lockdown level should be given the policy that is in place, as determined by the closed-loop feedback controller.
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spelling pubmed-86755482021-12-29 Optimized Lockdown Strategies for Curbing the Spread of COVID-19: A South African Case Study IEEE Access Biomedical Engineering To curb the spread of COVID-19, many governments around the world have implemented tiered lockdowns with varying degrees of stringency. Lockdown levels are typically increased when the disease spreads and reduced when the disease abates. A predictive control approach is used to develop optimized lockdown strategies for curbing the spread of COVID-19. The strategies are then applied to South African data. The South African case is of interest as the South African government has defined five distinct levels of lockdown, which serves as a discrete control input. An epidemiological model for the spread of COVID-19 in South Africa was previously developed, and is used in conjunction with a hybrid model predictive controller to optimize lockdown management under different policy scenarios. Scenarios considered include how to flatten the curve to a level that the healthcare system can cope with, how to balance lives and livelihoods, and what impact the compliance of the population to the lockdown measures has on the spread of COVID-19. The main purpose of this article is to show what the optimal lockdown level should be given the policy that is in place, as determined by the closed-loop feedback controller. IEEE 2020-11-11 /pmc/articles/PMC8675548/ /pubmed/34976564 http://dx.doi.org/10.1109/ACCESS.2020.3037415 Text en This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License. For more information, see https://creativecommons.org/licenses/by-nc-nd/4.0/ https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License. For more information, see https://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Biomedical Engineering
Optimized Lockdown Strategies for Curbing the Spread of COVID-19: A South African Case Study
title Optimized Lockdown Strategies for Curbing the Spread of COVID-19: A South African Case Study
title_full Optimized Lockdown Strategies for Curbing the Spread of COVID-19: A South African Case Study
title_fullStr Optimized Lockdown Strategies for Curbing the Spread of COVID-19: A South African Case Study
title_full_unstemmed Optimized Lockdown Strategies for Curbing the Spread of COVID-19: A South African Case Study
title_short Optimized Lockdown Strategies for Curbing the Spread of COVID-19: A South African Case Study
title_sort optimized lockdown strategies for curbing the spread of covid-19: a south african case study
topic Biomedical Engineering
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675548/
https://www.ncbi.nlm.nih.gov/pubmed/34976564
http://dx.doi.org/10.1109/ACCESS.2020.3037415
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