Upper Urinary Tract Urothelial Carcinoma With Squamous, Glandular, and Sarcomatoid Variants in a Horseshoe Kidney: A Novel Case Report and Literature Review

Horseshoe kidney is a congenital anomaly, which consists of fusion of the lower poles of the kidneys. Cancer in a horseshoe kidney is common, possibly because of the increased risk of chronic obstruction, renal calculi, and recurrent urinary infection. We report a case of a 64-year-old male with a h...

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Autores principales: Fikri, Jehad, Almalki, Abdullah M, Almalki, Sattam A, Murad, Muradi, Makhdoum, Sara, Hassan, Fadil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675583/
https://www.ncbi.nlm.nih.gov/pubmed/34956755
http://dx.doi.org/10.7759/cureus.19627
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author Fikri, Jehad
Almalki, Abdullah M
Almalki, Sattam A
Murad, Muradi
Makhdoum, Sara
Hassan, Fadil
author_facet Fikri, Jehad
Almalki, Abdullah M
Almalki, Sattam A
Murad, Muradi
Makhdoum, Sara
Hassan, Fadil
author_sort Fikri, Jehad
collection PubMed
description Horseshoe kidney is a congenital anomaly, which consists of fusion of the lower poles of the kidneys. Cancer in a horseshoe kidney is common, possibly because of the increased risk of chronic obstruction, renal calculi, and recurrent urinary infection. We report a case of a 64-year-old male with a horseshoe kidney who presented to our hospital with gross hematuria and flank pain, which was highly suggestive of pyelonephritis. Comprehensive workup and imaging were performed and showed an extremely rare form of tumor consisting of three histological variants: squamous, glandular, and sarcomatoid. To the best of our knowledge, this is the first case reported with these three histological variants in a horseshoe kidney.
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spelling pubmed-86755832021-12-23 Upper Urinary Tract Urothelial Carcinoma With Squamous, Glandular, and Sarcomatoid Variants in a Horseshoe Kidney: A Novel Case Report and Literature Review Fikri, Jehad Almalki, Abdullah M Almalki, Sattam A Murad, Muradi Makhdoum, Sara Hassan, Fadil Cureus Pathology Horseshoe kidney is a congenital anomaly, which consists of fusion of the lower poles of the kidneys. Cancer in a horseshoe kidney is common, possibly because of the increased risk of chronic obstruction, renal calculi, and recurrent urinary infection. We report a case of a 64-year-old male with a horseshoe kidney who presented to our hospital with gross hematuria and flank pain, which was highly suggestive of pyelonephritis. Comprehensive workup and imaging were performed and showed an extremely rare form of tumor consisting of three histological variants: squamous, glandular, and sarcomatoid. To the best of our knowledge, this is the first case reported with these three histological variants in a horseshoe kidney. Cureus 2021-11-16 /pmc/articles/PMC8675583/ /pubmed/34956755 http://dx.doi.org/10.7759/cureus.19627 Text en Copyright © 2021, Fikri et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Fikri, Jehad
Almalki, Abdullah M
Almalki, Sattam A
Murad, Muradi
Makhdoum, Sara
Hassan, Fadil
Upper Urinary Tract Urothelial Carcinoma With Squamous, Glandular, and Sarcomatoid Variants in a Horseshoe Kidney: A Novel Case Report and Literature Review
title Upper Urinary Tract Urothelial Carcinoma With Squamous, Glandular, and Sarcomatoid Variants in a Horseshoe Kidney: A Novel Case Report and Literature Review
title_full Upper Urinary Tract Urothelial Carcinoma With Squamous, Glandular, and Sarcomatoid Variants in a Horseshoe Kidney: A Novel Case Report and Literature Review
title_fullStr Upper Urinary Tract Urothelial Carcinoma With Squamous, Glandular, and Sarcomatoid Variants in a Horseshoe Kidney: A Novel Case Report and Literature Review
title_full_unstemmed Upper Urinary Tract Urothelial Carcinoma With Squamous, Glandular, and Sarcomatoid Variants in a Horseshoe Kidney: A Novel Case Report and Literature Review
title_short Upper Urinary Tract Urothelial Carcinoma With Squamous, Glandular, and Sarcomatoid Variants in a Horseshoe Kidney: A Novel Case Report and Literature Review
title_sort upper urinary tract urothelial carcinoma with squamous, glandular, and sarcomatoid variants in a horseshoe kidney: a novel case report and literature review
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675583/
https://www.ncbi.nlm.nih.gov/pubmed/34956755
http://dx.doi.org/10.7759/cureus.19627
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