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Endocrine Disorder in Patients With Craniopharyngioma

Craniopharyngioma is an intracranial congenital epithelial tumor growing along the pathway of the embryonic craniopharyngeal tube. The main clinical symptoms of patients with craniopharyngioma include high intracranial pressure, visual field defect, endocrine dysfunction, and hypothalamic dysfunctio...

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Detalles Bibliográficos
Autores principales: Zhou, Zihao, Zhang, Sheng, Hu, Fangqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675636/
https://www.ncbi.nlm.nih.gov/pubmed/34925209
http://dx.doi.org/10.3389/fneur.2021.737743
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author Zhou, Zihao
Zhang, Sheng
Hu, Fangqi
author_facet Zhou, Zihao
Zhang, Sheng
Hu, Fangqi
author_sort Zhou, Zihao
collection PubMed
description Craniopharyngioma is an intracranial congenital epithelial tumor growing along the pathway of the embryonic craniopharyngeal tube. The main clinical symptoms of patients with craniopharyngioma include high intracranial pressure, visual field defect, endocrine dysfunction, and hypothalamic dysfunction. At present, the preferred treatment remains the surgical treatment, but the recovery of endocrine and hypothalamic function following surgery is limited. In addition, endocrine disorders often emerge following surgery, which seriously reduces the quality of life of patients after operation. So far, research on craniopharyngioma focuses on ways to ameliorate endocrine dysfunction. This article reviews the latest research progress on pathogenesis, manifestation, significance, and treatment of endocrine disorders in patients with craniopharyngioma.
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spelling pubmed-86756362021-12-17 Endocrine Disorder in Patients With Craniopharyngioma Zhou, Zihao Zhang, Sheng Hu, Fangqi Front Neurol Neurology Craniopharyngioma is an intracranial congenital epithelial tumor growing along the pathway of the embryonic craniopharyngeal tube. The main clinical symptoms of patients with craniopharyngioma include high intracranial pressure, visual field defect, endocrine dysfunction, and hypothalamic dysfunction. At present, the preferred treatment remains the surgical treatment, but the recovery of endocrine and hypothalamic function following surgery is limited. In addition, endocrine disorders often emerge following surgery, which seriously reduces the quality of life of patients after operation. So far, research on craniopharyngioma focuses on ways to ameliorate endocrine dysfunction. This article reviews the latest research progress on pathogenesis, manifestation, significance, and treatment of endocrine disorders in patients with craniopharyngioma. Frontiers Media S.A. 2021-12-02 /pmc/articles/PMC8675636/ /pubmed/34925209 http://dx.doi.org/10.3389/fneur.2021.737743 Text en Copyright © 2021 Zhou, Zhang and Hu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Zhou, Zihao
Zhang, Sheng
Hu, Fangqi
Endocrine Disorder in Patients With Craniopharyngioma
title Endocrine Disorder in Patients With Craniopharyngioma
title_full Endocrine Disorder in Patients With Craniopharyngioma
title_fullStr Endocrine Disorder in Patients With Craniopharyngioma
title_full_unstemmed Endocrine Disorder in Patients With Craniopharyngioma
title_short Endocrine Disorder in Patients With Craniopharyngioma
title_sort endocrine disorder in patients with craniopharyngioma
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675636/
https://www.ncbi.nlm.nih.gov/pubmed/34925209
http://dx.doi.org/10.3389/fneur.2021.737743
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