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Macrophage uptake of oxidized and acetylated low-density lipoproteins and generation of reactive oxygen species are regulated by linear stiffness of the growth surface

Macrophages are key players in the development of atherosclerosis: they scavenge lipid, transform into foam cells, and produce proinflammatory mediators. At the same time, the arterial wall undergoes profound changes in its mechanical properties. We recently showed that macrophage morphology and pro...

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Detalles Bibliográficos
Autores principales: Gruber, Erika J., Aygun, Ali Y., Leifer, Cynthia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675690/
https://www.ncbi.nlm.nih.gov/pubmed/34914760
http://dx.doi.org/10.1371/journal.pone.0260756