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Effects of noise and time delay on E2F's expression level in a bistable Rb‐E2F gene’s regulatory network

The bistable Rb‐E2F gene regulatory network plays a central role in regulating cellular proliferation‐quiescence transition. Based on Gillespie's chemical Langevin method, the stochastic bistable Rb‐E2F gene’s regulatory network with time delays is proposed. It is found that under the moderate...

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Detalles Bibliográficos
Autores principales: Kirunda, John Billy, Yang, Lijian, Lu, Lulu, Jia, Ya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675803/
https://www.ncbi.nlm.nih.gov/pubmed/33881232
http://dx.doi.org/10.1049/syb2.12017

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