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Genetic mapping reveals Nfkbid as a central regulator of humoral immunity to Toxoplasma gondii

Protective immunity to parasitic infections has been difficult to elicit by vaccines. Among parasites that evade vaccine-induced immunity is Toxoplasma gondii, which causes lethal secondary infections in chronically infected mice. Here we report that unlike susceptible C57BL/6J mice, A/J mice were h...

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Detalles Bibliográficos
Autores principales: Souza, Scott P., Splitt, Samantha D., Sànchez-Arcila, Juan C., Alvarez, Julia A., Wilson, Jessica N., Wizzard, Safuwra, Luo, Zheng, Baumgarth, Nicole, Jensen, Kirk D. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8675933/
https://www.ncbi.nlm.nih.gov/pubmed/34871323
http://dx.doi.org/10.1371/journal.ppat.1010081